Epidemiological study of primary intracranial tumors: A regional survey in Kumamoto Prefecture in the southern part of Japan
Epidemiological study of primary intracranial tumors: A regional survey in Kumamoto Prefecture in the southern part of Japan
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DOI：
10.3171/jns.1996.84.6.0946
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发表时间：
1996-06-01
影响因子：
4.1
通讯作者：
Ushio, Y
中科院分区：
文献类型：
--
作者：
Kuratsu, JI;Ushio, Y
这项调查包括熊本县1117名居民，他们在1989至1994年间被诊断出患有原发性颅内肿瘤。所有病例均记录了年龄、性别、肿瘤类型和诊断日期；79%的诊断经组织学证实。年龄调整后的总发病率为每年每10万人9.47人。在男性中，年龄调整后的发病率为8.24/10万/年，细分为胶质瘤2.36例，脑膜瘤1.56例，垂体瘤1.46例，神经鞘瘤0.99例。在女性中，可比的总体发病率为10.7；其中脑膜瘤的发病率为3.95，胶质瘤为2.04，垂体瘤为2.16，神经鞘瘤为0.75。脑膜瘤是最常见的肿瘤，经年龄调整后的年均发病率为每10万人2.76人。在70至79岁的女性中，脑膜瘤的发病率最高，为每10万人中有13.02人。胶质瘤的发病率最高(每10万名男性中有5.71人，每10万名女性中有5.29人)见于60至69岁的患者。脑膜瘤、垂体腺瘤和恶性淋巴瘤在女性中发生率较高(男性/女性比率分别为0.39、0.68和0.81)。另一方面，胶质瘤、神经鞘瘤和生殖细胞肿瘤更多发生在男性(男性/女性比例分别为1.16、1.32和4.29)。脑膜瘤和生殖细胞肿瘤倾向于表现出性别特异性。
This survey consists of 1117 residents of Kumamoto Prefecture who were diagnosed with primary intracranial tumors between 1989 and 1994. Age, sex, tumor type, and date of diagnosis were recorded in all cases; 79% of the diagnoses were confirmed histologically. The overall age-adjusted incidence rate was 9.47 per 100,000 population per year. Among males, the age-adjusted incidence rate was 8.24 per 100,000 per year, and the breakdown included 2.36 gliomas, 1.56 meningiomas, 1.46 pituitary tumors, and 0.99 neurinomas. Among females, the comparable overall rate was 10.7; that included a rate of 3.95 for meningiomas, 2.04 for gliomas, 2.16 for pituitary tumors, and 0.75 for neurinomas. Meningiomas were the most common tumor, with an average annual age-adjusted incidence of 2.76 per 100,000 population. The highest incidence of meningiomas was 13.02 per 100,000 among women aged 70 to 79 years. The highest incidence of gliomas (5.71 per 100,000 males and 5.29 per 100,000 females) was seen in patients between 60 and 69 years of age. Meningiomas, pituitary adenomas, and malignant lymphomas occurred at a higher rate in females (male/female ratio: 0.39, 0.68, and 0.81, respectively). On the other hand, gliomas, neurinomas, and germ-cell tumors occurred more often in males (male/female ratio: 1.16, 1.32, and 4.29, respectively). Meningiomas and germ-cell tumors tended to exhibit gender specificity.