What is the most relevant standard of success in assisted reproduction?: The value of cryopreservation on cumulative pregnancy rates per single oocyte retrieval should not be forgotten.
What is the most relevant standard of success in assisted reproduction?: The value of cryopreservation on cumulative pregnancy rates per single oocyte retrieval should not be forgotten.
复制标题
辅助生殖成功的最相关标准是什么？：不应忘记冷冻保存对单个卵母细胞取出的累积妊娠率的价值。
DOI：
10.1093/humrep/deh446
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发表时间：
2004
影响因子：
6.1
通讯作者：
Mika Gissler
中科院分区：
文献类型：
--
作者：
Aila Tiitinen;C. Hydén;Mika Gissler
体外受精成功的最相关标准一直被广泛讨论。最佳标准应同时反映风险方面和治疗的有效性。对于这对夫妇来说，最重要的参数是每个启动周期的最终累积递送率。即使治疗周期的长期跟踪在实践中是困难的，我们也要强调，应更加重视胚胎冷冻，以便最大限度地提高试管受精/ICSI周期的效率。在选择性单胚胎移植周期计划中，胚胎冷冻保存的贡献可能会导致累积交付率达到50%。在芬兰，通过良好的冷冻保存计划，可以实施单一胚胎移植。这一战略的效果体现在辅助生殖后双胞胎分娩比例的下降，2002年为13.9%，以及全国医学出生登记中多胞胎比例的下降。
The most relevant standard of success in IVF has been discussed widely. An optimal standard should reflect both the risk aspects and the effectiveness of the treatment. The most important parameter for the couple is the ultimate cumulative delivery rate per started cycle. Even if the long-term follow-up of the treatment cycles is difficult in practice, we would stress that more emphasis should be given to embryo freezing, in order to maximize the efficiency of the IVF/ICSI cycles. The contribution of embryo cryopreservation in elective single embryo transfer cycle programmes may result in a cumulative delivery rate of >50%. In Finland, the implementation of single embryo transfer has been possible with good cryopreservation programmes. The effect of this strategy has been seen in a decrease in the proportion of twin deliveries after assisted reproduction, being 13.9% for 2002, as well as a reduction of the proportion of multiple births in the nationwide Medical Birth Registry.