How the contrast gain control modifies the frequency responses of cat retinal ganglion cells.
How the contrast gain control modifies the frequency responses of cat retinal ganglion cells.
复制标题
对比度增益控制如何改变猫视网膜神经节细胞的频率响应。
DOI：
10.1113/jphysiol.1981.sp013856
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Victor,JD
中科院分区：
文献类型：
--
作者：
Shapley,RM;Victor,JD
1.提出了对比度对猫视网膜神经节细胞一阶频率响应影响的模型。该模型由几个级联的低通滤波器（“漏积分器”）和一个单级负反馈组成。2.该模型中时间常数和组件增益的值被选择为近似（具有最小平方偏差）实验测量的一阶频率响应。在用于分析的实验中，视觉刺激是由正弦曲线的总和调制的正弦光栅。3.对于X细胞和Y细胞，低通滤波器级联的总增益和时间常数对对比度不敏感。4.在所有细胞中，负反馈回路的增益带宽积随着对比度的增加而显著增加。5.在感受野周边刺激对中心点的一阶频率响应的影响与光栅实验中增加对比度的影响相同。在所有情况下，负反馈回路的增益带宽积是受外周刺激影响的唯一模型参数。6.对于位于感受野周边的两个条，研究了非线性求和的类似效果。7.对比度增益控制机制的这种分析与视网膜功能的其他模型进行了比较。
1. A model is proposed for the effect of contrast on the first‐order frequency responses of cat retinal ganglion cells. The model consists of several cascaded low pass filters ('leaky integrators') followed by a single stage of negative feed‐back. 2. Values of time constants and gain of the components in this model were chosen to approximate (with least‐squared deviation) experimentally measured first‐order frequency responses. In the experiments used for the analysis, the visual stimulus was a sine grating modulated by a sum of sinusoids. 3. For both X cells and Y cells, the over‐all gain and the time constants of the cascade of low pass filters were insensitive to contrast. 4. In all cells, the gain‐bandwidth product of the negative feed‐back loop was markedly increased with increasing contrast. 5. The effect of stimulation in the periphery of the receptive fields on the first‐order frequency response to a centrally placed spot was identical to the effect of increasing contrast in the grating experiments. In all cases, the gain‐bandwidth product of the negative feed‐back loop was the only model parameter affected by peripheral stimulation. 6. A similar effect of non‐linear summation was investigated for two bars located in the receptive field periphery. 7. This analysis of the contrast gain control mechanism is compared with other models of retinal function.