Work schedules and 11-year progression of carotid atherosclerosis in middle-aged Finnish men.
Work schedules and 11-year progression of carotid atherosclerosis in middle-aged Finnish men.
复制标题
芬兰中年男性的工作安排和 11 年颈动脉粥样硬化进展。
DOI：
10.1002/ajim.22388
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发表时间：
2015
影响因子：
3.5
通讯作者：
Krause,Niklas
中科院分区：
文献类型：
--
作者：
Wang,Aolin;Arah,OnyebuchiA;Kauhanen,Jussi;Krause,Niklas
ObjectivesThis study investigated the relationship between different work schedules and progression of carotid atherosclerosis，a early indicator of cardiovascular disease（CVD）.MethodsWe studied 621 men，ageing 42-60 years，in the prospective Kuopio Ischemic Heart Disease Risk Factor Study cohort.使用多变量回归调整22个协变量，包括在随访过程中的总工作时间，我们评估了基线工作时间表与超声评估的颈动脉内膜中层厚度（IMT）的11年进展的相关性，以及它们与预先存在的CVD的变化。分别与白天工作者相比，周末工作者的颈动脉粥样硬化进展更快[相对变化率（RCR）= 1.05，95%CI：1.00-1.09]。这一比例更高的男性中有预先存在的cvod.ConclusionsWeekend轮班，超过标准的白天工作，似乎加速颈动脉粥样硬化进展的中年芬兰男性，特别是那些与预先存在的CVD。Am. J. Ind. Med. 58：1-13，2015。© 2014 Wiley Periodicals，Inc.
ObjectivesThis study investigated the relationship between different work schedules and progression of carotid atherosclerosis, an early indicator of cardiovascular disease (CVD).MethodsWe studied 621 men, aged 42–60 years, in the prospective Kuopio Ischemic Heart Disease Risk Factor Study cohort. Using multivariable regressions adjusting for 22 covariates including total time worked during follow‐up, we evaluated the associations of baseline work schedules with 11‐year progression of ultrasonographically assessed carotid intima‐media thickness (IMT), and their variation by preexisting CVD.ResultsStandard daytime work, weekend shifts, and evening/night/rotating shifts were associated with 31%, 37%, and 33% increases in IMT, respectively. Compared to daytime workers, weekend workers experienced a faster progression of carotid atherosclerosis [relative change ratio (RCR) = 1.05, 95% CI: 1.00–1.09)]. This ratio was higher among men who had preexisting CVD.ConclusionsWeekend shifts, more than standard daytime work, appear to accelerate carotid atherosclerosis progression among middle‐aged Finnish men, especially those with pre‐existing CVD. Am. J. Ind. Med. 58:1–13, 2015. © 2014 Wiley Periodicals, Inc.