Response to dehydration in elderly patients in long-term care
Response to dehydration in elderly patients in long-term care
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DOI：
10.1007/bf03339616
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发表时间：
1997-10-01
期刊：
影响因子：
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通讯作者：
Davies, I
中科院分区：
文献类型：
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作者：
ONeill, PA;Duggan, J;Davies, I
长期护理的老年患者血浆渗透压（pOSM）较高，相关死亡率增加。在这些患者中，我们检查了pOSM、口渴（视觉模拟量表，VAS）和精氨酸加压素（AVP）对16小时脱水和2小时补液的反应。12例患者随机分为A、B组。A组进行两周液体平衡监测，B组不进行液体平衡监测。在第0、7和13天进行VAS、pOSM和AVP的单次测量。在研究开始时（第1天）和两周结束时（第14天），在两组中进行脱水试验。A组和B组之间无显著差异，因此提供了两组合并的结果。脱水期间pOSM和VAS均显著增加，补液期间两个变量均显著下降[F（9，99）= 18.69，p
Elderly patients in long-term care have a high plasma osmolality (pOSM) and associated increased mortality. In these patients, we examined pOSM, thirst (visual analogue scale, VAS) and arginine vasopressin (AVP) response to 16-hour dehydration and 2-hour rehydration. Twelve patients were randomly divided into two groups (A & B). Group A had their fluid balance monitored for two weeks, group B did not. Single measurements of VAS, pOSM and AVP were conducted on days 0, 7 and 13. Dehydration tests were conducted in both groups at the start of the study (DAY 1), and at the end of the two-week period (DAY 14). There were no significant differences between group A and B, so the results are presented for the two groups combined. There was a significant increase in both pOSM and VAS during dehydration, and a significant fall in both variables during rehydration [F (9,99) = 18.69, p