Incidence and hospitalization rates of varicella and herpes tester before varicella vaccine introduction: a baseline assessment of the shifting epidemiology of varicella disease
Incidence and hospitalization rates of varicella and herpes tester before varicella vaccine introduction: a baseline assessment of the shifting epidemiology of varicella disease
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DOI：
10.1097/00006454-200107000-00002
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发表时间：
2001-07-01
影响因子：
3.6
通讯作者：
Guess, H
中科院分区：
文献类型：
--
作者：
Coplan, P;Black, S;Guess, H
背景北方加州Kaiser Permanente医疗保健计划（KPMCP）正在进行一项为期15年的水痘疫苗上市后对水痘疾病年龄分布影响的评估。我们报告了在疫苗引入前进行的水痘和疱疹测试仪的年龄特异性发病率和住院率的基线评估。为了评估水痘的年发病率，在随机抽样的8000名5 - 19岁的青年中进行了电话调查，1994年水痘住院和疱疹测试仪的年发病率使用KPMCP的计算机数据库进行了评估。水痘的年发病率在5- 9岁、10- 14岁和15- 19岁年龄组分别为10.3%、1.9%和1.2%。水痘和试验者的住院率在整个KPMCP成员中分别为2.6和2.1/10万人年。水痘发病率在15岁至15岁年龄组中非洲裔美国人高于白人。水痘率在5至9岁和10至14岁年龄组中与1972年至1978年、1980年至1988年和1990年至1992年进行的其他已发表研究的比率相似;然而，15至19岁的比率比同一年龄组的已发表比率高2至4倍。
Background. A 15-year postmarketing evaluation of the impact of varicella vaccine on the age distribution of varicella disease is being conducted at Kaiser Permanente Medical Care Program, Northern California (KPMCP), We report on a baseline assessment of the age-specific incidence and hospitalization rates of varicella and herpes tester that was conducted before vaccine introduction.Methods. To assess the annual incidence of varicella, a telephone survey was conducted in a random sample of similar to 8000 youths 5 to 19 years of age, The annual incidence of hospitalizations for varicella and herpes tester in 1994 was assessed with the use of the computerized database at KPMCP.Results. Varicella annual incidence was 10.3% in 5- to 9-year-olds, 1.9% in 10- to 14-year-olds and 1.2% in the 15- to 19-year age groups, respectively, Hospitalization rates among the entire KPMCP membership were 2.6 and 2.1 per 100 000 person years for varicella and tester, respectively. Varicella incidence in the 15- to Is-year age group was higher among African-Americans than among Caucasians.Conclusions. Varicella rates were similar in the 5- to 9- and 10- to 14-year age groups to rates from other published studies conducted in 1972 to 1978, 1980 to 1988 and 1990 to 1992; however, the rate in 15- to 19-year-olds was 2 to 4 times higher than published rates in the same age category.