Addressing the post-acute sequelae of SARS-CoV-2 infection: a multidisciplinary model of care.
Addressing the post-acute sequelae of SARS-CoV-2 infection: a multidisciplinary model of care.
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DOI：
10.1016/s2213-2600(21)00385-4
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发表时间：
2021-11
期刊：
影响因子：
--
通讯作者：
Turnbull AE
中科院分区：
文献类型：
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作者：
Parker AM;Brigham E;Connolly B;McPeake J;Agranovich AV;Kenes MT;Casey K;Reynolds C;Schmidt KFR;Kim SY;Kaplin A;Sevin CM;Brodsky MB;Turnbull AE
截至 2021 年 7 月 31 日，SARS-CoV-2 已感染全球近 2 亿人。就长期健康影响的复杂性和受影响的人数而言，生存负担日益沉重。据报告，轻度和重度急性 COVID-19 患者（包括入住重症监护病房 (ICU) 的患者）均出现持续症状。关于 SARS-CoV-2 感染 (PASC) 急性后遗症的早期报告表明，最常见的症状包括疲劳、呼吸困难、咳嗽、头痛、味觉或嗅觉丧失以及认知或心理健康障碍。这些跨越身体、认知和心理健康领域的复杂、多因素的损伤需要采取协调的、多学科的方法来管理。数十年来对重症监护后综合症患者的多方面需求和护理模式的研究为 PASC 诊所的发展提供了框架，以满足住院和非住院的 COVID-19 幸存者的迫切需求。此类诊所还可以提供一个平台，对 PASC 的自然史和治疗干预的潜在益处进行严格研究。
As of July 31, 2021, SARS-CoV-2 had infected almost 200 million people worldwide. The growing burden of survivorship is substantial in terms of the complexity of long-term health effects and the number of people affected. Persistent symptoms have been reported in patients with both mild and severe acute COVID-19, including those admitted to the intensive care unit (ICU). Early reports on the post-acute sequelae of SARS-CoV-2 infection (PASC) indicate that fatigue, dyspnoea, cough, headache, loss of taste or smell, and cognitive or mental health impairments are among the most common symptoms. These complex, multifactorial impairments across the domains of physical, cognitive, and mental health require a coordinated, multidisciplinary approach to management. Decades of research on the multifaceted needs of and models of care for patients with post-intensive care syndrome provide a framework for the development of PASC clinics to address the immediate needs of both hospitalised and non-hospitalised survivors of COVID-19. Such clinics could also provide a platform for rigorous research into the natural history of PASC and the potential benefits of therapeutic interventions.