StrainInfo introduces electronic passports for microorganisms
StrainInfo introduces electronic passports for microorganisms
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DOI：
10.1016/j.syapm.2013.11.002
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发表时间：
2014-02-01
影响因子：
3.4
通讯作者：
Dawyndt, Peter
中科院分区：
文献类型：
--
作者：
Verslyppe, Bert;De Smet, Wim;Dawyndt, Peter
微生物学以存放在生物资源中心(BRCs)的生物材料为基础，作为合作研究的参考框架。BRC分配所谓的菌株编号来标记沉积的材料，并负责材料的长期保存和全球分发。培养的微生物可以存放在多个BRCs中，BRCs也可以相互交换它们的持有物。因此，许多不同的菌株编号可以附着在来自同一分离物的生物材料上。在实践中，这种材料被认为是等效的，可以互换使用。这意味着在搜索时需要使用所有相同的菌株编号才能找到关于给定生物材料的信息。StraInfo为微生物引入了菌株护照：关于给定微生物菌株的已知信息的统一概述。它包含所有已知的等效应变号以及有关该菌株的交换历史、序列和相关文献的信息。每个护照都有一个关联的应变浏览器，可以直接访问护照所基于的底层BRC目录条目。分类群护照、序列护照和文献护照的实施方式类似。除了为人类用户服务的网页外，集成信息还以机器可读的格式提供，有助于自动化、大规模的分析。StraInfo被设想为一个集成微生物信息的开放平台。该平台可以利用网上可获得的大量电子信息，为微生物研究的新方法奠定基础。培训信息可从http://www.StrainInfo.net.获得(C)2013年爱思唯尔股份有限公司。版权所有。
Microbiology builds upon biological material deposited in biological resource Centers (BRCs) as a reference framework for collaborative research. BRCs assign so-called strain numbers to label the deposited material and are responsible for long-term preservation and worldwide distribution of the material. Cultured microorganisms can be deposited into multiple BRCs and BRCs also mutually exchange their holdings. As a result, many different strain numbers can be attached to biological material that stems from the same isolate. In practice, this material is considered equivalent and used interchangeably. This implies that finding information on given biological material requires all equivalent strain numbers to be used when searching.StrainInfo introduces strain passports for microorganisms: a uniform overview of information known about a given microbial strain. It contains all known equivalent strain numbers and information on the exchange history, sequences and related literature of the strain. Each passport has an associated strain browser that gives direct access to the underlying BRC catalog entries on which the passport was based. Taxon, sequence and literature passports are implemented in a similar manner. In addition to web pages that serve human users, integrated information is also offered in machine readable formats useful for automated, large-scale analysis.StrainInfo is envisioned to be an open platform integrating microbial information. This platform can form the basis for new methods of microbiological research, leveraging the vast amount of electronic information available online. StrainInfo is available from http://www.StrainInfo.net. (C) 2013 Elsevier GmbH. All rights reserved.