Like mother, like microbe: human milk oligosaccharide mediated microbiome symbiosis.
Like mother, like microbe: human milk oligosaccharide mediated microbiome symbiosis.
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DOI：
10.1042/bst20191144
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发表时间：
2020-06-30
影响因子：
3.9
通讯作者：
Townsend SD
中科院分区：
文献类型：
--
作者：
Chambers SA;Townsend SD
从分娩后不久开始，并持续到我们的一生，肠道微生物群与我们的代谢和神经程序协同进化。这种共生关系受到宿主和环境因素（包括饮食和生活方式）之间复杂相互作用的调节。毫不奇怪，这种微生物群落的发展对健康和保健至关重要。在这篇有针对性的综述中，我们研究了从出生到两岁的肠道微生物组，以表征人乳低聚糖在微生物植物群早期形成中的作用。
Starting shortly after parturition, and continuing throughout our lifetime, the gut microbiota coevolves with our metabolic and neurological programming. This symbiosis is regulated by a complex interplay between the host and environmental factors, including diet and lifestyle. Not surprisingly, the development of this microbial community is of critical importance to health and wellness. In this targeted review, we examine the gut microbiome from birth to two years of age to characterize the role human milk oligosaccharides play in early formation of microbial flora.