Ischaemic-heart-disease mortality and dietary intake of calcium.
Ischaemic-heart-disease mortality and dietary intake of calcium.
复制标题
缺血性心脏病死亡率和膳食钙摄入量。
DOI：
10.1016/s0140-6736(73)91808-4
复制
发表时间：
1973
期刊：
影响因子：
168.9
通讯作者：
E. Knox
中科院分区：
文献类型：
--
作者：
E. Knox
对英格兰和威尔士不同地区不同年份的心脏病标化死亡率(S.M.R.S)与膳食中多种营养素的摄入量进行了相关分析。钙摄入量显示出强烈的负相关，与硬水和软水地区死亡率之间的变化一致。在排除钙的影响后，脂肪和维生素D的摄入量都与死亡率的剩余变化呈正相关。良好的病理生理学解释是可用的。然而，对不同营养素和S.M.R.S与一系列其他疾病死亡的相关性的检查显示，一个一致的模式并不是缺血性心脏病所特有的。缺血性心脏病的地区性营养关联最好的解释可能是间接影响。
Correlation analysis was carried out between the standardised mortality ratios (S.M.R.S) for ischæmic heart-disease in different regions of England and Wales in different years and dietary intakes of a number of nutrients. Calcium intakes showed a strong negative correlation, consistent with variations between mortalities in hard and soft water areas. Fat and vitamin-D intakes both showed positive associations with residual variation of the mortality-rates after the effects of calcium had been excluded. Good pathophysiological explanations are available. However, examination of the correlations between different nutrients and S.M.R.S related to deaths from a range of other diseases showed a consistent pattern which was not at all specific for ischæmic heart-disease. The regional nutrient associations of ischæmic heart-disease are probably best explained as indirect effects.