Pregnancy-associated anaplastic large-cell lymphoma of the breast: A rare mimic of ductal carcinoma

Pregnancy-associated anaplastic large-cell lymphoma of the breast: A rare mimic of ductal carcinoma
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DOI:
10.1002/dc.20442
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发表时间:
2006-04-01
影响因子:
1.3
通讯作者:
Moreira, AL
Moreira, AL
中科院分区:
医学4区
文献类型:
--
作者:
Iyengar, P;Reid-Nicholson, M;Moreira, AL

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间变性大细胞淋巴瘤(ALCL)是一种罕见的T细胞淋巴瘤,通常见于儿童和年轻人。它已被描述在许多网站;然而,乳房是最不常见的位置之一。我们在此报告一位36岁孕妇的乳房发生ALCL的病例。据我们所知,这是第二个这样的情况下,在英国文学。我们想强调ALCL的细胞学和组织学特征,因为这种情况最初被误诊为导管癌。与其他肿瘤的鉴别诊断也进行了讨论。这个病例强调了三重检测的重要性,以及在乳腺肿瘤治疗中细针穿刺结果与核心活检结果相关的必要性。
Anaplastic large-cell lymphoma (ALCL) is a rare T-cell lymphoma typically seen in children and young adults. It has been described in numerous sites; however, the breast is one of the least common locations. We herein report a case of ALCL arising in the breast of a 36-yr-old pregnant woman. To our knowledge this is the second such case in the English literature. We would like to highlight the cytologic and histologic features of ALCL, as this ease was initially misdiagnosed as a ductal carcinoma. Differential diagnosis with other tumors is also discussed. This case serves to emphasize the importance of the triple test, and the need for correlation of fine-needle aspiration findings with core biopsy findings in breast tumor management.