Carpal tunnel syndrome incidence in a general population
Carpal tunnel syndrome incidence in a general population
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DOI：
10.1212/wnl.58.2.289
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发表时间：
2002-01-22
期刊：
影响因子：
9.9
通讯作者：
Giacchi, M
中科院分区：
文献类型：
--
作者：
Mondelli, M;Giannini, F;Giacchi, M
目的：确定意大利中部限制地区普通人群腕管综合征（CTS）的发病率。研究方法：根据临床症状和正中神经远端传导速度延迟确定新诊断的CTS病例的前瞻性研究。在1991年至1998年的8年期间，在托斯卡纳（意大利）第7地方卫生区锡耶纳地区通过肌电图服务确定了病例。这个地区有12万人口。结果：在8年的时间里，确定了3,142例（79.7%女性和20.3%男性;平均年龄55岁;范围13至97岁）。年平均粗发病率为329例/10万人年，标准化发病率为276例。性别特异性发病率为男性139例，女性506例。在研究期间，男性的平均年发病率适度但显著增加，而女性的平均年发病率保持不变。妇女的特定年龄发病率随着年龄的增长而逐渐增加，在50至59岁之间达到高峰，之后下降。在男性中，存在双峰分布，峰值在50至59岁之间和70至79岁之间。农村和工业区的粗发病率以及年龄和性别特异性发病率高于城市地区。结论：锡耶纳地区的发病率约为罗切斯特地区（明尼苏达州）的三倍，与马什菲尔德（威斯康星州）的发病率相似。美国报告的不同结果可能取决于病例纳入标准和高危人群的职业活动。
Objective: To determine the incidence of carpal tunnel syndrome (CTS) in a general population of a restricted area in the middle part of Italy. Methods: Prospective study to identify cases of CTS, newly diagnosed on the basis of clinical symptoms and delay in distal conduction velocity of the median nerve. In the 8-year period from 1991 to 1998, cases were identified by electromyographic services in the Siena area of Local Health District No. 7 of Tuscany (Italy). This area has a population of 120,000. Results: In the 8-year period, 3,142 cases (79.7% women and 20.3% men; mean age, 55 years; range, 13 to 97 years) were identified. The mean annual crude incidence was 329 cases per 100,000 person-years, and the standardized incidence was 276. The sex-specific incidences were 139 for men and 506 for women. The mean annual incidence for men increased moderately but significantly during the study period, whereas that for women remained constant. The age-specific incidence for women increased gradually with age, reaching a peak between 50 and 59 years, after which it declined. In men, there was a bimodal distribution with peaks between 50 and 59 years and between 70 and 79 years. Rural and industrial areas had higher crude and age- and sex-specific incidences than did urban areas. Conclusions: The incidence in the Siena area is about threefold that reported in the Rochester area (Minnesota) and is similar to that of Marshfield (Wisconsin). The different results with respect to US reports may depend on case inclusion criteria and occupational activities of the population at risk.