Characterization of the mineral content of a physical sunscreen emulsion and its distribution onto human stratum corneum
Characterization of the mineral content of a physical sunscreen emulsion and its distribution onto human stratum corneum
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DOI：
10.1111/j.1467-2494.1997.tb00175.x
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发表时间：
1997-01-01
影响因子：
2.3
通讯作者：
Hemmerle, J.
中科院分区：
文献类型：
--
作者：
Dussert, A.-S.;Gooris, E.;Hemmerle, J.
使用物理防晒霜时。保护和美观方面直接关系到颗粒大小和矿物分布在皮肤上。这些研究的目的是表征进入特定防晒乳液组成的不同矿物原料，并评估防晒剂在人体角质层表面的分布。x射线衍射揭示了tio2和ZnO晶体的晶体学特征。测定了粒径最大、形状各异的氧化锌晶体长度和纵横比的频率分布。扫描和透射电子显微镜揭示了结构信息。本研究报告的结果明确了配方中涉及的氧化物颗粒的特征，并显示出沿皮肤不规则地形的令人满意的矿物分布。未见细胞内渗透。
When using physical sunscreens. protection and aesthetic aspects are directly related to particle size and mineral distribution onto skin. These investigations aimed to characterize the different mineral raw materials entering into the composition of a specific sunscreen emulsion and to assess the distribution of the sunscreen agents at the surface of human stratum corneum. X-ray diffractometry revealed the crystallographic features of the TiO-2 and ZnO crystals. Frequency distributions of crystal length and aspect ratio were determined for the zinc oxide which presented the largest particle size and varying shapes. Scanning and transmission electron microscopy disclosed structural information. The results reported in this study specify the characteristics of the oxide particles involved in the formulation and show a satisfactory mineral distribution along the irregular topography of the skin. No intracellular penetration was noted.