Light physical activity determined by a motion sensor decreases insulin resistance, improves lipid homeostasis and reduces visceral fat in high-risk subjects: PreDiabEx study RCT
Light physical activity determined by a motion sensor decreases insulin resistance, improves lipid homeostasis and reduces visceral fat in high-risk subjects: PreDiabEx study RCT
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DOI：
10.1038/ijo.2013.224
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发表时间：
2014-08-01
影响因子：
4.9
通讯作者：
Keinanen-Kiukaanniemi, S.
中科院分区：
文献类型：
--
作者：
Herzig, K-H;Ahola, R.;Keinanen-Kiukaanniemi, S.
目的：探讨体力活动(PA)阈值对2型糖尿病(T2D)高危患者血糖、胰岛素、血脂及体脂组成的影响。干预：对113名口服糖耐量试验中血糖异常的男女受试者进行调查。将78例年龄为58.8±10.4岁、体重指数为31.7±5.3 kg m(-2)的受试者随机分为干预组和对照组。干预包括3个月的有监督步行(60min，每周3次)。结果：每天超过80%的步数集中在0.3~0.7g的加速水平(步行2~3 km h(-1))，干预组为5870步，对照组为4434步(P
OBJECTIVE: To examine physical activity (PA) thresholds affecting glucose, insulin and lipid concentrations and body fat composition in high-risk patients for type 2 diabetes (T2D).INTERVENTION: A total of 113 subjects of both genders having abnormal glucose levels in the oral glucose tolerance test were contacted. A total of 78 subjects with age 58.8 +/- 10.4 years and body mass index 31.7 +/- 5.3 kg m(-2) were randomly assigned to intervention and control groups. Intervention consisted of a supervised walking (60 min three times weekly) for 3 months. All the subjects received standard care for PA and weight reduction and wore an accelerometer during the whole wakeful time.RESULTS: Over 80% of the daily steps clustered at an acceleration level of 0.3-0.7 g (2-3 km h(-1) of walking) and were 5870 in the intervention and 4434 in the control group (P