Correction of coherence gate curvature in high numerical aperture optical coherence imaging.
Correction of coherence gate curvature in high numerical aperture optical coherence imaging.
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DOI：
10.1364/ol.35.003120
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发表时间：
2010-09-15
期刊：
影响因子：
3.6
通讯作者：
Boppart SA
中科院分区：
文献类型：
--
作者：
Graf BW;Adie SG;Boppart SA
提出了一种校正光谱域高na光学相干成像系统中扫描路径长度变化引起的相干门曲率的方法。这些变化导致光学相干层析成像中的曲率伪影，有效地限制了光学相干显微镜（OCM）的视场。在这里，我们证明了相干门曲率可以通过从校准图像中恢复解析信号的相位来测量和校正。该相位信息可以直接用于处理OCM图像，允许相干门曲率以及任何顺序的系统色散，以计算有效的方式进行校正。我们还讨论了各种图像质量指标的使用，可用于调整校准相位，以保持组织中的相干和共聚焦门对齐。
We present a method for correcting coherence gate curvature caused by scanning-induced path length variations in spectral-domain high-NA optical coherence imaging systems. These variations cause curvature artifacts in optical coherence tomography and effectively restrict the field of view in optical coherence microscopy (OCM). Here we show that the coherence gate curvature can be measured and corrected by recovering the phase of the analytic signal from a calibration image. This phase information can be used directly to process OCM images allowing the coherence gate curvature, as well as any order of system dispersion, to be corrected in a computationally efficient manner. We also discuss the use of various image quality metrics that can be used to adjust the calibrated phase in order to keep the coherence and confocal gates aligned in tissue.