Nonattendance is still the main limitation for the effectiveness of screening for cervical cancer in the Netherlands
Nonattendance is still the main limitation for the effectiveness of screening for cervical cancer in the Netherlands
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DOI：
10.1002/ijc.22114
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发表时间：
2006-11-15
影响因子：
6.4
通讯作者：
van Ballegooijen, Marjolein
中科院分区：
文献类型：
--
作者：
Bos, Anita B.;Rebolj, Matejka;van Ballegooijen, Marjolein
尽管大规模宫颈癌筛查在荷兰已经开展了 20 多年，但每年仍有 700 名女性被诊断出患有这种癌症（每 100,000 人中有 9 人）。我们调查了这些案例，以评估进一步提高该计划有效性的机会。我们使用荷兰国家病理档案（包括宫颈细胞学和组织学结果）分析了 1994 年至 1997 年间诊断患有宫颈癌的女性的筛查历史。超过一半的病例以前没有进行过预防性宫颈涂片检查，另外 30% 的病例由于年龄原因从未被邀请参加该计划。根据目前超过 70% 的筛查参与率，我们估计未来三分之二患有浸润性宫颈癌的荷兰女性将未接受筛查或筛查不足。我们的结论是，增加筛查参与度比缩短筛查间隔、增加年龄范围或进行灵敏度更高的筛查测试更有可能进一步降低宫颈癌发病率。 (c) 2006 Wiley-Liss, Inc.
Although mass screening for cervical cancer has been operational for more than 2 decades in the Netherlands, 700 women are still diagnosed with this cancer each year (9 per 100,000). We investigated these cases, in order to evaluate opportunities to further increase the effectiveness of the programme. We analyzed the screening history of women diagnosed with cervical cancer between 1994-1997 using the Dutch national pathology file that includes cervical cytology and histological results. More than half of the cases did not have previous preventive cervical smears, and another 30% had never been invited to the programme because of their age. In the future, we estimate that two thirds of all Dutch women with invasive cervical cancer will be unscreened or under-screened, based on current screening participation of more than 70%. We conclude that increasing screening participation has much more potential for further reducing cervical cancer incidence than reducing the screening interval, increasing the age range or having a screening test with higher sensitivity. (c) 2006 Wiley-Liss, Inc.