Commentary: considerations on the characterization and treatment of self-injurious behavior.
Commentary: considerations on the characterization and treatment of self-injurious behavior.
复制标题
评论：关于自伤行为的特征和治疗的考虑。
DOI：
10.1023/a:1005507708636
复制
发表时间：
2000
影响因子：
3.9
通讯作者：
Ernst,M
中科院分区：
文献类型：
--
作者：
Ernst,M
1脑成像科，国家药物滥用研究所，5500内森休克驱动器，巴尔的摩，马里兰州21224。这些尺寸（表IV），以捕捉SIB的关键方面。例如，暗示习得行为的方面（例如，自愿的、操作的、情绪的）预期涉及皮质异常（高级认知功能的神经基质），而仅限于运动功能障碍的方面指向异常的运动系统（例如，基底神经节）。自闭症儿童可以在不同时间或同时表现出这两种行为。很有可能，治疗将需要不同的SIB的每个实体：行为干预的学习行为，和运动功能障碍的药理学方法。在人类行为的系统化表征的另一个应用是它在动物研究中的使用。能否开发出基于人类观察的动物模型？一个例子可能是与社会隔离相关的SIB，其特征在于自我刺激行为，并在隔离的猴子中观察到（参见Jones & Barraclough，1978）。由于明显的物种差异，这种策略很难应用，
1 Brain Imaging Section, National Institute on Drug Abuse, 5500 Nathan Shock Drive, Baltimore, Maryland 21224. such dimensions (Table IV) to capture critical aspects of SIB. For example, aspects that suggest learned behavior (eg, voluntary, operant, emotional) are expected to involve cortical abnormalities (neural substrates of higher cognitive function), whereas aspects that are restricted to motor dysfunction point to abnormal motor systems (eg, basal ganglia). A child with autism can present both types of behavior at different times or concurrently. It is very likely that treatment will need to differ for each entity of SIB: behavioral intervention for the learned behavior, and pharmacological approach for the motor dysfunction.Another application of the systematized characterization of behavior in humans is its use in animal research. Can animal models based on human observation be developed? One example might be SIB associated with social isolation, which has been characterized as a self-stimulation behavior, and has been observed in monkeys placed in isolation (for review see Jones & Barraclough, 1978). This strategy is difficult to apply due to obvious species differences that pre-