CORTICAL-NEURONS PROJECTING TO CERVICAL AND LUMBAR ENLARGEMENTS OF SPINAL-CORD IN YOUNG AND ADULT RHESUS-MONKEYS
CORTICAL-NEURONS PROJECTING TO CERVICAL AND LUMBAR ENLARGEMENTS OF SPINAL-CORD IN YOUNG AND ADULT RHESUS-MONKEYS
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DOI：
10.1016/0014-4886(78)90240-6
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发表时间：
1978-01-01
影响因子：
5.3
通讯作者：
LAVAIL, JH
中科院分区：
文献类型：
--
作者：
BIBER, MP;KNEISLEY, LW;LAVAIL, JH
在5只幼猴和1只成年猴的颈段和腰段前角多次注射辣根过氧化物酶(HRP)后，用逆行传递法观察到向脊髓的颈段和腰段投射的皮质神经元。在中央前回和中央后回、第5区内侧和背侧的吻侧半部、第6区内侧的扣带沟和外侧沟的第2躯体感觉区有体细胞定位排列的标记神经元。所有HRP阳性神经元均局限于皮质V层或与第5层对应的深度，在皮质层被冰冻或切片伪影模糊的区域。虽然标记神经元的横截面积在每个视野内差异很大，但在腿部的标记神经元比在中央前回的臂部更多。HRP阳性神经元在第1、2躯体感觉区和第5区内侧均为中等大小，在初级运动区和辅助运动区以及第5区背侧均为中等或较大神经元。
Cortical neurons projecting to cervical and lumbar segments of the spinal cord in 5 young and 1 adult monkeys were identified using the retrograde transport method following multiple unilateral injections of horseradish peroxidase (HRP) into the anterior horn at cervical and lumbar levels of the spinal cord. Somatotopically organized labeled neurons were found in the precentral and postcentral gyri, the rostral half of both the medial and dorsal aspects of area 5, the cingulate sulcus within the medial aspect of area 6, and the 2nd somatosensory area within the lateral sulcus. All HRP-positive neurons were confined to cortical layer V or to a depth corresponding to the 5th layer in regions where delineation of cortical layers were obscured due to freezing or sectioning artifacts. Although cross-sectional areas of labeled neurons varied widely within each field, more large labeled neurons were present in the leg than in the arm subdivision of the precentral gyrus. HRP-positive neurons in the 1st and 2nd somatosensory areas as well as those in the medial aspect of area 5 were of medium size, and those in the primary and supplementary motor areas as well as those within the dorsal aspect of area 5 were of medium or larger size.