AdaDiag: Adversarial Domain Adaptation of Diagnostic Prediction with Clinical Event Sequences.
AdaDiag: Adversarial Domain Adaptation of Diagnostic Prediction with Clinical Event Sequences.
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DOI:
10.1016/j.jbi.2022.104168
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发表时间:
2022-10
影响因子:
4.5
通讯作者:
Bui, Alex A. T.
中科院分区:
文献类型:
--
作者:
Zhang, Tianran;Chen, Muhao;Bui, Alex A. T.
Early detection of heart failure (HF) can provide patients with the opportunity for more timely intervention and better disease management, as well as efficient use of healthcare resources. Recent machine learning (ML) methods have shown promising performance on diagnostic prediction using temporal sequences from electronic health records (EHRs). In practice, however, these models may not generalize to other populations due to dataset shift. Shifts in datasets can be attributed to a range of factors such as variations in demographics, data management methods, and healthcare delivery patterns. In this paper, we use unsupervised adversarial domain adaptation methods to adaptively reduce the impact of dataset shift on cross-institutional transfer performance. The proposed framework is validated on a next-visit HF onset prediction task using a BERT-style Transformer-based language model pre-trained with a masked language modeling (MLM) task. Our model empirically demonstrates superior prediction performance relative to non-adversarial baselines in both transfer directions on two different clinical event sequence data sources.
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DOI:
10.1093/jamia/ocw112
发表时间:
2017-03-01
期刊:
Journal of the American Medical Informatics Association : JAMIA
影响因子:
--
作者:
Choi E;Schuetz A;Stewart WF;Sun J
通讯作者:
Sun J
影响因子:
2.9
作者:
Bao G;Zhuang N;Tong L;Yan B;Shu J;Wang L;Zeng Y;Shen Z
通讯作者:
Shen Z
影响因子:
5.9
作者:
Gupta, Priyanka;Malhotra, Pankaj;Shroff, Gautam
通讯作者:
Shroff, Gautam
影响因子:
37.8
作者:
Goldberger, AL;Amaral, LAN;Stanley, HE
通讯作者:
Stanley, HE
DOI:
10.1177/1178222617712994
发表时间:
2017
期刊:
Biomedical informatics insights
影响因子:
--
作者:
Desautels T;Calvert J;Hoffman J;Mao Q;Jay M;Fletcher G;Barton C;Chettipally U;Kerem Y;Das R
通讯作者:
Das R