Endobronchial ultrasound transbronchial needle aspiration in older people
Endobronchial ultrasound transbronchial needle aspiration in older people
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DOI：
10.1111/ggi.12043
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发表时间：
2013-10-01
影响因子：
3.3
通讯作者：
Hasegawa, Yoshinori
中科院分区：
文献类型：
--
作者：
Okachi, Shotaro;Imai, Naoyuki;Hasegawa, Yoshinori
目的 支气管内超声经支气管针吸活检 (EBUS-TBNA) 的实用性和安全性最近已确定，但尚无研究评估衰老是否会增加该手术的风险。在本研究中，我们旨在评估 EBUS-TBNA 在老年患者中的有效性和安全性。方法对 2008 年至 2011 年在日本名古屋大学医院接受 EBUS-TBNA 的 109 例患者的医疗记录和数据库进行回顾性审查。所有患者均在咪达唑仑轻度镇静下接受支气管镜检查。共有 34 名患者年龄在 70 岁或以上（老年组），75 名患者年龄在 69 岁或以下（年轻组）。我们分析了两组患者的特征、临床参数的变化、咪达唑仑和利多卡因的使用剂量、手术时间、活检淋巴结的地理数据、诊断率和并发症。结果老年组合并症较多。老年组中的四名患者（11.8%）表现不佳（2-3）。老年组的基线收缩压明显较高。术中部分临床参数（最低氧饱和度[SpO(2)]、SpO(2)降低、最大补氧量、收缩压升高、心率增加）两组间无统计学差异。老年患者的诊断表现与年轻患者相似。两组之间的并发症发生率没有差异。结论EBUS-TBNA在老年人中的安全性和有效性与年轻人相当。老年老年国际 2013； 13：986-992。
AimThe usefulness and safety of endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) have been established recently, but no study has evaluated whether or not aging increases the risk of the procedure. In the present study, we aimed to assess the usefulness and safety of EBUS-TBNA in older patients.MethodsThe medical records and database of 109 patients who received EBUS-TBNA between 2008 and 2011 at Nagoya University Hospital, Nagoya, Japan were reviewed retrospectively. All patients underwent bronchoscopy under light sedation with midazolam. A total of 34 patients were aged 70 years or older (the older group) and 75 were aged 69 years or younger (the younger group). We analyzed patients' characteristics, changes of clinical parameters, usage doses of midazolam and lidocaine, procedure duration, geographic data of biopsied lymph nodes, diagnostic yield, and complications in both groups.ResultsThere were more comorbidities in the older group. Four patients (11.8%) in the older group had poor performance status (2-3). Systolic blood pressure at baseline was significantly higher in the older group. There were no statistical differences between the two groups in some clinical parameters (minimum oxygen saturation [SpO(2)], reduction in SpO(2), maximum oxygen supplementation, elevation of systolic blood pressure, increase of heart rate) during the procedure. Diagnostic performance in older patients was similar to that found in younger patients. There was no difference in the frequency of complications between both groups.ConclusionSafety and usefulness of EBUS-TBNA in older people were comparable with those in younger people. Geriatr Gerontol Int 2013; 13: 986-992.