Biochemical studies in suicide victims: current findings and future implications.
Biochemical studies in suicide victims: current findings and future implications.
复制标题
自杀受害者的生化研究:当前发现和未来影响。
DOI:
10.1111/j.1943-278x.1989.tb00364.x
复制
发表时间:
1989
影响因子:
3.2
通讯作者:
Stanley,B
中科院分区:
文献类型:
--
作者:
Stanley,M;Stanley,B
This chapter contains a review of some of the relevant neurochemical findings in postmortem suicide studies. As the results of these studies are described, we try to indicate their relative strengths and weaknesses, as well as to provide an overview regarding the advantages and short-comings of a given technique or approach. One important issue that should be addressed at the outset is the diagnostic heterogeneity of those individuals who commit suicide. Data indicate that approximately 50% of suicide victims are diagnosed as depressed; the remaining cases carry a variety of diagnoses, including schizophrenia, personality disorders, and alcoholism (Barraclough, Bunch, Nelson, & Sainsbury, 1974; Dorpat & Ripley, 1960; Robins, Murphy, Wilkinson, Gassner, & Kayes, 1959). Thus, it is of both theoretical and practical importance to note that suicide victims typically represent a diagnostically heterogeneous group of individuals. With regard to biochemical findings within this population, the diagnostic heterogeneity suggests that differencesin neurochemistry may be more closely related to suicidal behavior than to any one diagnostic subgroup. Consequently suicide studies that restrict their enrollment to a single