PEUTZ-JEGHERS SYNDROME WITH OVARIAN SEX CORD TUMOR WITH ANNULAR TUBULES AND CERVICAL ADENOMA-MALIGNUM

PEUTZ-JEGHERS SYNDROME WITH OVARIAN SEX CORD TUMOR WITH ANNULAR TUBULES AND CERVICAL ADENOMA-MALIGNUM
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DOI:
10.1016/0090-8258(91)90234-v
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发表时间:
1991-07-01
影响因子:
4.7
通讯作者:
SOROSKY, JI
SOROSKY, JI
中科院分区:
医学2区
文献类型:
--
作者:
PODCZASKI, E;KAMINSKI, PF;SOROSKY, JI

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A patient with Peutz-Jeghers syndrome, a sex cord tumor with annular tubules, and an initially unrecognized adenoma malignum of the cervix is described. The patient presented with a mucinous adenocarcinoma in the vaginal apex. Review of the hysterectomy slides demonstrated an adenoma malignum of the cervix. In addition to a microscopic sex cord tumor with annular tubules of the right ovary, the left ovary contained mucinous cystadenomas. Adenoma malignum remains a difficult diagnosis and is frequently made only after hysterectomy for a presumed benign indication; pathology frequently demonstrates a deeply invasive, unusually well-differentiated adenocarcinoma of the cervix. Patients with Peutz-Jeghers syndrome need careful clinical and cytologic follow-up to exclude such lesions.