Event-related potentials to tones in the absence and presence of sleep spindles
Event-related potentials to tones in the absence and presence of sleep spindles
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DOI：
10.1046/j.1365-2869.1997.00033.x
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发表时间：
1997-06-01
影响因子：
4.4
通讯作者：
Kok, A
中科院分区：
文献类型：
--
作者：
Elton, M;Winter, O;Kok, A
本研究主要关注睡眠纺锤波存在和不存在时音调的事件相关电位。在一个适应课程之后，研究人员对六名本科生进行了一整晚的实验研究。对每个受试者的音调刺激的事件相关电位取平均值。在音调前后2秒没有睡眠纺锤波的实验和有纺锤波活动的实验中，分别确定了平均值。电压分布图和波形的多变量分析都产生了这些条件之间的显着差异，这可以被视为更高的初始正分量和在主轴存在时的平均时间内持续的正分量。光谱分析表明，这一结果不能仅仅归因于剩余的西格玛活动在纺锤体目前的平均值。除了抑制的神经生理学模型所提出的，这些结果可能为睡眠纺锤波在人类中的功能作用提供见解。
The present study focused on event-related potentials to tones in the presence and absence of sleep spindles. Six undergraduates were studied throughout an experimental night, following an adaptation session. The event-related potentials to tone stimuli were averaged for each subject. Separate averages were determined for trials on which no sleep spindle occurred 2 s before or after a tone and trials in which spindle activity was present. Both voltage distribution maps and multivariate analysis of the waveforms produced significant differences between these conditions, which could be seen as a higher initial positive component and sustained positivity over the averaged epoch in the presence of spindles. Spectral analysis indicated that this result could not solely be ascribed to residual sigma activity in the spindle-present average. The results may provide insights into the functional role of sleep spindles in humans in addition to that suggested by a neurophysiological model of inhibition.