The effect of pharmacotherapist characteristics on treatment outcome in panic disorder.
The effect of pharmacotherapist characteristics on treatment outcome in panic disorder.
复制标题
药物治疗师特征对恐慌症治疗结果的影响。
DOI：
10.1002/da.10087
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发表时间：
2003
影响因子：
7.4
通讯作者：
Woods,ScottW
中科院分区：
文献类型：
--
作者：
Gorman,JackM;Martinez,JoséM;Goetz,Raymond;Huppert,JonathanD;Ray,Susan;Barlow,DavidH;Shear,MKatherine;Woods,ScottW
大量研究表明，心理治疗师的个体特征会影响精神疾病心理社会治疗的结果，但很少有研究表明药物治疗是否也是如此。在一项比较惊恐障碍的心理社会治疗和药物治疗的多中心研究中，我们评估了精神科医生的年龄、经验年数和性别等特征是否影响抗惊恐药物丙咪嗪的治疗结果。通过多元回归和逻辑回归分析对 8 名精神科医生的数据进行了检查，他们总共治疗了 57 名惊恐障碍患者。更多的医生经验（以完成住院医师培训后的年数为单位）与在两个主要二分测量之一（临床整体印象改善量表）和九个连续测量评级量表中的六个上对丙咪嗪的更好反应相关。精神科医生年龄与结果之间以及精神科医生性别与结果之间也存在关联，但衡量标准较少。尽管这些是事后分析，在多中心研究最初设计时并未计划，因此有关精神科医生特征的可用信息存在局限性，但研究结果表明，即使在采用特定方案和单一药物的临床试验中，医生经验也可能影响患者的治疗结果。抑郁与焦虑 17:88–93, 2003。© 2003 Wiley-Liss, Inc.
A large number of studies suggest that individual characteristics of psychotherapists affect the outcome of psychosocial treatments for psychiatric illness, but little work has been done to see if this is also the case for pharmacotherapy. In the context of a multicenter study that compared psychosocial and medication treatments for panic disorder, we assessed whether such characteristics as age of the psychiatrist, number of years of experience, and gender influence the outcome of treatment with the antipanic drug imipramine. Data were examined by multiple and logistic regression analyses for eight psychiatrists who treated a total of 57 patients with panic disorder. More physician experience, measured as years since completing residency, was associated with better response to imipramine on one of two main dichotomous measures (the Clinical Global Impression‐Improvement Scale) and on six of nine continuous measure rating scales. Associations between psychiatrist age and outcome and between psychiatrist gender and outcome were also present but on fewer measures. Although these are post‐hoc analyses that were not planned when the multicenter study was originally designed and therefore there are limitations in the information available about the psychiatrists' characteristics, the findings suggest that even in the context of a clinical trial that employs a specific protocol and single medication, physician experience may influence patient outcome. Depression and Anxiety 17:88–93, 2003. © 2003 Wiley‐Liss, Inc.