Gene Activity dependent on Chromosome Synapsis in the Polytene Chromosomes of Drosophila melanogaster

Gene Activity dependent on Chromosome Synapsis in the Polytene Chromosomes of Drosophila melanogaster
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果蝇多线染色体中染色体联会依赖的基因活性

DOI:
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发表时间:
1967
期刊:
影响因子:
64.8
通讯作者:
M. Ashburner
M. Ashburner
中科院分区:
综合性期刊1区
文献类型:
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作者:
M. Ashburner

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在研究高等生物中基因活性的控制时,研究得比较深入的现象之一是双翅目多线染色体的“膨化”现象,这种现象已被证明是基因活性的一种表达1。摇蚊属和果蝇属幼虫和蛹前期发育过程中喷烟的变化模式在一定程度上受到蜕皮激素的影响2,3。有证据表明,这种激素的作用是间接的,通过控制细胞和核sap的离子组成起作用4 -6。
ONE of the more intensively studied phenomena used in investigating the control of gene activity in higher organisms is the “puffing” of the polytene chromosomes of Diptera, a phenomenon which has been shown to be an expression of gene activity1. The changing pattern of puffs during larval and prepupal development in Chironomus and Drosophila is influenced, to a certain extent, by the hormone ecdysone2,3. There is evidence that the effect of this hormone is indirect, acting by way of a control of the ionic composition of the cell and nuclear sap4–6.