Gene Activity dependent on Chromosome Synapsis in the Polytene Chromosomes of Drosophila melanogaster
Gene Activity dependent on Chromosome Synapsis in the Polytene Chromosomes of Drosophila melanogaster
复制标题
果蝇多线染色体中染色体联会依赖的基因活性
作者:
M. Ashburner
ONE of the more intensively studied phenomena used in investigating the control of gene activity in higher organisms is the “puffing” of the polytene chromosomes of Diptera, a phenomenon which has been shown to be an expression of gene activity1. The changing pattern of puffs during larval and prepupal development in Chironomus and Drosophila is influenced, to a certain extent, by the hormone ecdysone2,3. There is evidence that the effect of this hormone is indirect, acting by way of a control of the ionic composition of the cell and nuclear sap4–6.