Synthesis of C4-fluorinated solamins and their growth inhibitory activity against human cancer cell lines
Synthesis of C4-fluorinated solamins and their growth inhibitory activity against human cancer cell lines
复制标题
DOI：
10.1016/j.bmcl.2008.10.069
复制
发表时间：
2008-12-15
影响因子：
2.7
通讯作者：
Yamori, Takao
中科院分区：
文献类型：
--
作者：
Kojima, Naoto;Hayashi, Hiromi;Yamori, Takao
合成了抗肿瘤活性成分茄素的C4-氟代类似物，并研究了其对39种肿瘤细胞的抗肿瘤活性。C4-氟龙葵素对癌细胞系的生长抑制活性比龙葵素强。(C)2008爱思唯尔有限公司保留所有权利。
C4-Fluorinated analogues of solamin, an antitumor acetogenin, were synthesized and investigated for their antitumor activities against 39 tumor cell lines. C4-Fluorinated solamins showed more potent growth inhibitory activity against cancer cell lines than solamin. (C) 2008 Elsevier Ltd. All rights reserved.