Whole-colon investigation vs. flexible sigmoidoscopy for suspected colorectal cancer based on presenting symptoms and signs: a multicentre cohort study
Whole-colon investigation vs. flexible sigmoidoscopy for suspected colorectal cancer based on presenting symptoms and signs: a multicentre cohort study
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DOI：
10.1038/s41416-018-0335-z
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发表时间：
2019-01-22
影响因子：
8.8
通讯作者：
Atkin, Wendy
中科院分区：
文献类型：
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作者：
Cross, Amanda J.;Wooldrage, Kate;Atkin, Wendy
背景：怀疑结直肠癌（CRC）的患者通常接受结肠镜检查。如果近端癌症风险较低，可弯曲乙状结肠镜检查（FS）可能是首选。我们调查了哪些患者可以接受FS单独。方法：队列研究的7375例患者（>= 55岁）被称为可疑CRC的21家英国医院（2004-2007年），随后使用医院记录和癌症登记。我们计算了根据症状/体征和子部位诊断一种癌症所需的全结肠检查（NNE）的产量和数量。我们认为窄（血红蛋白
BACKGROUND: Patients with suspected colorectal cancer (CRC) usually undergo colonoscopy. Flexible sigmoidoscopy (FS) may be preferred if proximal cancer risk is low. We investigated which patients could undergo FS alone.METHODS: Cohort study of 7375 patients (>= 55 years) referred with suspected CRC to 21 English hospitals (2004-2007), followed using hospital records and cancer registries. We calculated yields and number of needed whole-colon examinations (NNE) to diagnose one cancer by symptoms/signs and subsite. We considered narrow (haemoglobin