Functional delineation of the human occipito-temporal areas related to face and scene processing - A PET study
Functional delineation of the human occipito-temporal areas related to face and scene processing - A PET study
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DOI：
10.1093/brain/123.9.1903
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发表时间：
2000-09-01
期刊：
影响因子：
14.5
通讯作者：
Zilles, K
中科院分区：
文献类型：
--
作者：
Nakamura, K;Kawashima, R;Zilles, K
通过使用PET测量区域脑血行，我们描绘了面孔和场景激活的枕颞区的作用。我们要求右利手正常被试以人脸图像为视觉刺激执行三个任务：在面孔熟悉/不熟悉辨别（FF）任务中，被试辨别朋友和同事的面孔和不熟悉面孔;在点位置辨别（DL）任务中，他们辨别了一张混乱的脸上红点的位置。在每个任务中的活动进行了比较，在控制固定（CF）任务，其中他们固定在没有视觉刺激的显示器的中心。DL任务激活了双侧枕叶皮质和后梭状回。在FD任务中，激活向前延伸到右侧梭状回和右侧颞下皮层。FF任务进一步激活了右颞极。为了检验由于面孔的激活是否是面孔特异性的，我们使用了一个场景熟悉/不熟悉的歧视（SF）的任务，在该任务中，受试者区分熟悉的场景从不熟悉的。我们的研究结果表明：（1）枕叶皮层和后梭状回对面孔、混叠面孔和场景具有非选择性反应，主要参与复杂视觉图像物理特征的提取;（ii）右颞下回/梭状回对面孔有选择性反应，但对非面孔刺激无反应，并参与与面孔知觉有关的视觉处理，而双侧海马旁回和顶枕交界处选择性地对场景作出反应，并参与与场景感知相关的处理;（iii）右颞极在熟悉的面孔和场景与不熟悉的面孔和场景的辨别过程中被激活，并可能参与熟悉物体的识别。
By measuring regional cerebral blood Row using PET, we delineated the roles of the occipito-temporal regions activated by faces and scenes. We asked right-handed normal subjects to perform three tasks using facial images as visual stimuli: in the face familiar/unfamiliar discrimination (FF) task, they discriminated the faces of their friends and associates from unfamiliar ones; in the face direction discrimination (FD) task, they discriminated the direction of each unfamiliar face; in the dot location discrimination (DL) task, they discriminated the location of a red dot on a scrambled face. The activity in each task was compared with that in the control fixation (CF) task, in which they fixated on the centre of a display without visual stimuli. The DL task activated the occipital cortices and posterior fusiform gyri bilaterally. During the FD task, the activation extended anteriorly in the right fusiform gyrus and laterally to the right inferior temporal cortex. The FF task further activated the right temporal pole. To examine whether the activation due to faces was face-specific, we used a scene familiar/unfamiliar discrimination (SF) task, in which the subjects discriminated familiar scenes from unfamiliar ones. Our results suggest that (i) the occipital cortices and posterior fusiform gyri non-selectively respond to faces, scrambled faces and scenes, and are involved mainly in the extraction of physical features of complex visual images; (ii) the right inferior temporal/fusiform gyrus responds selectively to faces but not to non-face stimuli and is involved in the visual processing related to face perception, whereas the bilateral parahippocampal gyri and parieto-occipital junctions respond selectively to scenes and are involved in processing related to scene perception; and (iii) the right temporal pole is activated during the discrimination of familiar faces and scenes from unfamiliar ones, and is probably involved in the recognition of familiar objects.