Laser-induced breakdown spectroscopy (LIBS): an overview of recent progress and future potential for biomedical applications
Laser-induced breakdown spectroscopy (LIBS): an overview of recent progress and future potential for biomedical applications
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DOI：
10.3109/03091902.2011.645946
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发表时间：
2012-02-01
影响因子：
--
通讯作者：
Miziolek, A. W.
中科院分区：
文献类型：
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作者：
Rehse, S. J.;Salimnia, H.;Miziolek, A. W.
激光诱导击穿光谱（LIBS）技术的发展使LIBS技术从元素分析技术发展为可用于分子复杂生物材料或临床标本的无试剂分析技术。LIBS技术的快速发展催生了越来越多的最近在同行评审期刊上发表的文章，这些文章一直证明LIBS能够快速检测，生化表征和分析，和/或准确识别各种生物，生物医学或临床样品。这些分析本质上是实时的，不需要样品制备，并提供高灵敏度和特异性。LIBS生物医学应用的概述旨在总结迄今为止已经进行的研究，并向医疗保健提供者提出几种可能的具体未来应用，如果成功实施，将对人类产生重大利益。
The recent progress made in developing laser-induced breakdown spectroscopy (LIBS) has transformed LIBS from an elemental analysis technique to one that can be applied for the reagentless analysis of molecularly complex biological materials or clinical specimens. Rapid advances in the LIBS technology have spawned a growing number of recently published articles in peer-reviewed journals which have consistently demonstrated the capability of LIBS to rapidly detect, biochemically characterize and analyse, and/or accurately identify various biological, biomedical or clinical samples. These analyses are inherently real-time, require no sample preparation, and offer high sensitivity and specificity. This overview of the biomedical applications of LIBS is meant to summarize the research that has been performed to date, as well as to suggest to health care providers several possible specific future applications which, if successfully implemented, would be significantly beneficial to humankind.