Accommodation, pupil diameter and myopia
Accommodation, pupil diameter and myopia
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DOI：
10.1111/j.1475-1313.2008.00611.x
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发表时间：
2009-01-01
影响因子：
2.9
通讯作者：
Radhakrishnan, Hema
中科院分区：
文献类型：
--
作者：
Charman, W. Neil;Radhakrishnan, Hema
同时测量青年组、成年近视组（n = 20）、成年近视组（年龄（平均+/- SD） 23.1 +/- 4.5岁，平均球面误差(MSE) -3.06 +/- 2.35 D，范围为-0.60 ~ -8.54 D）和成年近视组（平均年龄25.3 +/- 5.7岁，平均MSE -0.07 +/- 0.26 D，范围为-0.50 ~ +0.50 D）的稳态调节反应/刺激曲线和瞳孔直径。本研究的目的是探讨在近视组中，放松调节瞳孔直径更大而调节瞳孔缩小更弱的可能性。这种行为会导致近视组的视网膜图像相对更大的退化，即使两组在恒瞳直径和屈光调节滞后时的像差相同：这可能导致过度的轴向生长和进一步的近视发展。没有证据表明任何系统的屈光依赖性瞳孔特征或调节反应被发现。有趣的是，那些反应/刺激曲线斜率较高的受试者倾向于表现出更大的适应性瞳孔缩小，而与他们的屈光不正无关。
Concurrent measurements of steady-state accommodation response/stimulus curves and of pupil diameter were made in groups (n = 20) of young, adult myopes [age (mean +/- SD) 23.1 +/- 4.5 years, mean-sphere error (MSE) -3.06 +/- 2.35 D, range -0.60 to -8.54 D] and emmetropes (mean age 25.3 +/- 5.7 years, mean MSE -0.07 +/- 0.26 D, range -0.50 to +0.50 D). The aim of this study was to explore the possibilities that pupil diameters with relaxed accommodation were larger, and that accommodative miosis was weaker, in the myopic group. Such behaviour would lead to relatively greater degradation of the retinal images in the myopic group, even though aberrations at constant pupil diameter and dioptric accommodative lags in the two groups were the same: this might result in excessive axial growth and further myopia development. No evidence for any systematic refractive dependence of pupillary characteristics or accommodative responses was found. Interestingly, those subjects whose response/stimulus curves had a higher slope tended to display greater accommodative miosis, irrespective of their refractive error.