The impact of posttraumatic seizures on 1-year neuropsychological and psychosocial outcome of head injury.
The impact of posttraumatic seizures on 1-year neuropsychological and psychosocial outcome of head injury.
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创伤后癫痫发作对头部损伤一年神经心理学和心理社会结果的影响。
DOI：
10.1017/s1355617700001661
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Dikmen,SS
中科院分区：
文献类型：
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作者：
Haltiner,AM;Temkin,NR;Winn,HR;Dikmen,SS
本研究调查了 210 名成年人的创伤后癫痫发作和头部损伤严重程度与神经心理学表现和心理社会功能的关系，这些成年人在中度至重度创伤性头部损伤后 1 年后进行了前瞻性随访和评估。到 1 年随访时，18% (n = 38) 的患者经历了 1 次或多次晚期癫痫发作（即癫痫发作发生在创伤后 8 天或以上）。正如预期的那样，经历过晚期创伤后癫痫发作的头部受伤患者是那些头部受伤最严重的患者，与那些没有癫痫发作的患者相比，他们在神经心理学和社会心理测量方面的受损程度明显更严重。然而，在控制头部损伤严重程度的影响后，一年后神经心理学和心理社会结果与癫痫发作的函数没有显着差异。这些发现表明，创伤后癫痫发作长达一年的患者的较差结果很大程度上反映了导致癫痫发作的脑损伤的影响，而不是癫痫发作的影响。 （JINS，1996，2，494-504。）
This study examined the relationship of posttraumatic seizures and head injury severity to neuropsychological performance and psychosocial functioning in 210 adults who were prospectively followed and assessed 1 year after moderate to severe traumatic head injury. Eighteen percent (n = 38) of the patients experienced 1 or more late seizures (i.e., seizures occurring 8 or more days posttrauma) by the time of the 1-year followup. As expected, the head injured patients who experienced late posttraumatic seizures were those with the most severe head injuries, and they were significantly more impaired on the neuropsychological and psychosocial measures compared to those who remained seizure free. However, after the effects of head injury severity were controlled, there were no significant differences in neuropsychological and psychosocial outcome at 1 year as a function of having seizures. These findings suggest that worse outcomes in patients who develop posttraumatic seizures up to 1 year posttrauma largely reflect the effects of the brain injuries that cause seizures, rather than the effect of seizures. (JINS, 1996, 2, 494–504.)