Left prefrontal activation during episodic remembering: an event-related fMRI study
Left prefrontal activation during episodic remembering: an event-related fMRI study
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DOI：
10.1097/00001756-199810260-00032
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发表时间：
1998-10-26
期刊：
影响因子：
1.7
通讯作者：
D'Esposito, M
中科院分区：
文献类型：
--
作者：
Nolde, SF;Johnson, MK;D'Esposito, M
当前的主要理论将前额叶皮质(PFC)的大脑机制与离散事件记忆(情景记忆)联系起来，强调右侧PFC在提取过程中的作用。使用事件相关功能磁共振成像，我们发现在情景记忆过程中，左右两侧都有PFC活动，但只有左侧PFC活动与测试中所需的情景细节数量有关。我们认为，右PFC从属于相对简单的启发式认知过程，而左PFC被招募用于更多要求反思的、系统的过程。情节记忆通常需要这样的系统过程，在这种情况下，新招募的左翼和右翼一等兵。(C)1998年，Lippincott Williams&Wilkins。
THE major current theory relating brain mechanisms in prefrontal cortex (PFC) to memory for discrete events (episodic memory) emphasizes the role of right PFC during retrieval. Using event-related fMRI, we found both right and left PFC activity during episodic remembering, but only the left PFC activity was related to the amount of episodic detail required at test. We suggest that right PFC subserves relatively simple, heuristic, cognitive processes and that left PFC is recruited for more reflectively demanding, systematic, processes. Episodic remembering often requires such systematic processes and, under those circumstances, recruits left, as well as right, PFC. (C) 1998 Lippincott Williams & Wilkins.