A Facile Surface Functionalization Method for Polymers Using a Nonsolvent
A Facile Surface Functionalization Method for Polymers Using a Nonsolvent
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使用非溶剂进行聚合物的简便表面官能化方法
DOI：
10.1021/acsabm.0c00028
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发表时间：
2020
影响因子：
4.7
通讯作者：
K
中科院分区：
文献类型：
--
作者：
Hirata;T; Taneda;H; Nishio;K; Inutsuka;M; Yamada;NL; Nemoto;F; Minagawa;Y; Matsuno;H; Tanaka;K
对聚合物固体进行表面处理而不损害其本体性质是促进其更广泛应用的关键功能化策略。在这里，我们提出了一种简便的方法，使用非溶剂，可以微妙地改变或溶胀的聚合物表面改性。将聚（甲基丙烯酸甲酯）（PMMA）的薄膜浸入聚（2-甲氧基乙基丙烯酸酯）（PMEA）的甲醇溶液中。化学分析和中子反射仪的电子能谱显示，PMEA层上形成的PMMA膜的扩散界面。PMEA层在水中非常溶胀，并表现出抑制血清蛋白吸附和血小板粘附的能力。使用非溶剂的功能化技术也适用于其他聚合物固体如聚氨酯的表面。
Surface treatment of polymeric solids without impairing their bulk properties is a crucial functionalization strategy for the promotion of their wider application. We here propose a facile method using a nonsolvent which can subtly alter or swell the polymer surface to be modified. A thin film of poly(methyl methacrylate) (PMMA) was immersed in a methanol solution of poly(2-methoxyethyl acrylate) (PMEA). Electron spectroscopy for chemical analysis and neutron reflectometry revealed that a PMEA layer formed on the PMMA film with a diffused interface. The PMEA layer was very swollen in water and exhibited the ability to suppress serum protein adsorption and platelet adhesion on it. The functionalization technique using a nonsolvent was also applicable to the surface of other polymeric solids such as polyurethane.