Cognitive outcomes after psychotherapeutic interventions for major depression in older adults with executive dysfunction.
Cognitive outcomes after psychotherapeutic interventions for major depression in older adults with executive dysfunction.
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DOI：
10.1016/j.jagp.2013.11.002
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发表时间：
2014-12
影响因子：
7.2
通讯作者：
Arean, Patricia A.
中科院分区：
文献类型：
--
作者：
Mackin, R. Scott;Nelson, J. Craig;Delucchi, Kevin;Raue, Patrick;Byers, Amy;Barnes, Deborah;Satre, Derek D.;Yaffe, Kristine;Alexopoulos, George S.;Arean, Patricia A.
关键词：
本研究的目的是确定心理治疗对老年抑郁症（LLD）和执行功能障碍的认知功能的影响。221名60岁及以上的成年人参加了一项随机临床试验，比较了问题解决疗法（PST）和支持疗法（ST）对LLD的疗效。在基线、治疗12周后和治疗完成后24周，对执行功能、语言学习和记忆的7项测试的认知表现进行评价。在治疗后，具有显著信息处理速度成分的执行功能测量（Stroop色词测试; SCWT）的表现有所改善，F（1，312）= 8.50，p = 0.002，并且改善的表现与抑郁症状的减少相关，但与治疗类型无关。在12周的心理治疗后，执行功能、语言学习和记忆的其他指标没有显著变化。我们的研究结果表明，在心理治疗抑郁症的老年人与执行功能障碍的认知功能的改善可能是焦点，而不是分布在所有的认知领域。虽然先前的分析报告说，PST是上级ST在治疗抑郁症，这项分析表明，两种治疗方法之间没有差异，就改善认知功能。
The purpose of this study was to determine the impact of psychotherapy on cognitive functioning in older adults with late life depression (LLD) and executive dysfunction. 221 adults aged 60 years and older participated in a randomized clinical trial comparing the efficacy of Problem Solving Therapy (PST) and Supportive Therapy (ST) for LLD. Cognitive performance on 7 tests of executive functioning, verbal learning, and memory was evaluated at baseline, after 12 weeks of treatment, and at 24 weeks following the completion of treatment. Performance on a measure of executive functioning with a significant information processing speed component (Stroop Color Word test; SCWT) improved following treatment, F (1, 312) = 8.50, p = .002 and improved performance was associated with a reduction in depressive symptoms but not treatment type. Performance on other measures of executive functioning, verbal learning, and memory did not change significantly following 12 weeks of psychotherapy treatment. Our results suggest that improvements in cognitive functioning following psychotherapy treatment for depression in older adults with executive dysfunction are likely focal and not distributed across all cognitive domains. Although previous analyses reported that PST was superior to ST in the treatment of depression, this analysis indicated no difference between the two treatments with regard to improvements in cognitive functioning.
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