Negative BOLD differentiates visual imagery and perception
Negative BOLD differentiates visual imagery and perception
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DOI：
10.1016/j.neuron.2005.10.032
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发表时间：
2005-12-08
期刊：
影响因子：
16.2
通讯作者：
Pascual-Leone, A
中科院分区：
文献类型：
--
作者：
Amedi, A;Malach, R;Pascual-Leone, A
最近的研究强调视觉感知和视觉意象的神经基质之间的重叠。然而，想象和看到的主观体验明显不同。在这里，我们证明了通过 BOLD 功能磁共振成像测量的听觉皮层（以及在某种程度上体感和皮层下视觉结构）的失活可以明确区分视觉图像和视觉感知。在视觉意象过程中，听觉皮层的失活与视觉皮层的激活以及视觉意象主观生动度问卷（VVIQ）的得分呈负相关。对世界的感知需要融合多感官信息，以便在观看过程中，来自其他感官系统的信息会改变视觉皮层活动并塑造体验。我们认为，纯粹的视觉图像对应于视觉皮层区域的孤立激活，同时停用“不相关”的感觉处理，这可能会破坏我们的“心灵之眼”创建的图像。
Recent studies emphasize the overlap between the neural substrates of visual perception and visual imagery. However, the subjective experiences of imagining and seeing are clearly different. Here we demonstrate that deactivation of auditory cortex (and to some extent of somatosensory and subcortical visual structures) as measured by BOLD functional magnetic resonance imaging unequivocally differentiates visual imagery from visual perception. During visual imagery, auditory cortex deactivation negatively correlates with activation in visual cortex and with the score in the subjective vividness of visual imagery questionnaire (VVIQ). Perception of the world requires the merging of multisensory information so that, during seeing, information from other sensory systems modifies visual cortical activity and shapes experience. We suggest that pure visual imagery corresponds to the isolated activation of visual cortical areas with concurrent deactivation of "irrelevant" sensory processing that could disrupt the image created by our "mind's eye."