Neurochemical, physiological, and behavioral effects of bright light therapy on a cortically blind patient
Neurochemical, physiological, and behavioral effects of bright light therapy on a cortically blind patient
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DOI：
10.3109/00207459609000620
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发表时间：
1996-01-01
影响因子：
2.2
通讯作者：
Denbow, DM
中科院分区：
文献类型：
--
作者：
Parker, JS;Flory, RK;Denbow, DM
本研究评估了强光治疗对皮质性失明患者的影响。行为功能指标包括情绪评价、疲劳评价、食欲评价和定向评价。评估的生理指标包括血压和体温。分析血清5-HIAA和去甲肾上腺素（NE）水平。作为对照和随访，患者接受30分钟的红光照射（300勒克斯），30分钟的白光照射（10000勒克斯）进行治疗。高压液相色谱分析显示，雏鸟血清样品血清5-羟色胺（5-HT）无变化。然而，光处理后血液NE增加（红光：12.7 ng/ml，白光：43.5 ng/ml，红光：27.5 ng/ml）。数据分析显示，4项结果测量的基线和治疗评分存在显著差异。
The present study evaluated the effects of bright light therapy on a patient with cortical blindness. Behavioral indices of functioning included the appraisal of mood, fatigue, appetite and orientation. Physiological measures assessed were blood pressure and temperature. Blood serum samples were analyzed for 5-HIAA and norepinephrine (NE). For the control and follow-up, the patient was exposed to 30 minutes of red light (300-lux), and thirty minutes of white light (10,000-lux) was used for treatment. High-pressure liquid chromatography analyses of brood serum samples revealed no change in serotonin (5-HT). However, an increase in blood NE was indicated following light treatment (red light: 12.7 ng/ml, white light: 43.5 ng/ml and, red light: 27.5 ng/ml). Analysis of data revealed significant differences in baseline and treatment scores for 4 of the outcome measures.