Changes in cerebral blood flow velocity after release of intraoperative tourniquets in humans: a transcranial Doppler study.
Changes in cerebral blood flow velocity after release of intraoperative tourniquets in humans: a transcranial Doppler study.
复制标题
人类术中止血带释放后脑血流速度的变化：经颅多普勒研究。
DOI：
10.1213/00000539-199011000-00009
复制
发表时间：
1990
影响因子：
5.7
通讯作者：
A. Lam
中科院分区：
文献类型：
--
作者：
R. Hirst;T. A. Slee;A. Lam
使用经颅多普勒超声检查，对 5 名接受控制通气全身麻醉的患者进行下肢骨科手术，检查术中释放大腿止血带对大脑中动脉血流速度的影响。释放止血带后 4 +/- 1 分钟内，大脑中动脉血流速度从 52 +/- 6 (SEM) 显着增加至 82 +/- 24 cm/s（增加 58% +/- 13%），并在 7 分钟内保持显着升高。止血带放气后每次大脑中动脉血流速度与PETCO2均呈正线性相关（0.97大于或等于r大于或等于0.84，0.001大于P大于0.0001）。假设流速和流量之间存在线性关系，这些研究结果表明，术中止血带释放后脑血流量可能会显着增加，并且这种增加似乎主要依赖于二氧化碳。
The effect of release of intraoperative thigh tourniquets on velocity of blood flow in the middle cerebral artery was examined in five patients given general anesthesia with controlled ventilation for lower extremity orthopedic procedures using transcranial Doppler sonography. Middle cerebral artery blood flow velocity increased significantly from 52 +/- 6 (SEM) to 82 +/- 24 cm/s (an increase of 58% +/- 13%) within 4 +/- 1 min after tourniquet release and remained significantly elevated for 7 min. A positive linear correlation was found between middle cerebral artery blood flow velocity and PETCO2 on each occasion (0.97 greater than or equal to r greater than or equal to 0.84, 0.001 greater than P greater than 0.0001) after tourniquet deflation. Assuming a linear relationship between flow velocity and flow, these findings suggest that significant increase in cerebral blood flow can occur after intraoperative tourniquet release and that this increase appears to be mostly CO2-dependent.