Fibrodysplasia Ossificans Progressiva in the Cat
Fibrodysplasia Ossificans Progressiva in the Cat
复制标题
猫进行性骨化性纤维发育不良
DOI：
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发表时间：
1992
期刊：
影响因子：
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通讯作者：
K. Beck
中科院分区：
文献类型：
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作者：
B. Valentine;C. George;J. Randolph;L. Fuhrer;K. Beck
描述了患有进行性骨化性纤维发育不良的猫的临床、放射学、肌电图和病理学结果。还介绍了先前报道的五例这种猫科动物疾病的特征。这种疾病影响年轻到中年的两性猫。典型的临床特征包括步态进行性僵硬，伴有近端肢体肌肉组织增大。放射线检查显示受影响的肌肉组织内存在多种矿化密度。临床病程迅速，在两周至几个月内出现严重残疾。肌电图和病理结果表明，这是一种结缔组织疾病，主要影响肌外膜、肌腱和筋膜，并导致纤维血管结缔组织显着增殖，并伴有软骨样和骨化生。
Clinical, radiographic, electromyographic, and pathologic findings in a cat with fibrodysplasia ossificans progressiva are described. The features of five previously reported cases of this feline disorder are also presented. This disorder affects young adult to middle-aged cats of both sexes. Characteristic clinical features include progressive stiffness of gait, with enlargement of proximal limb musculature. Radiography reveals multiple mineralized densities within the affected musculature. The clinical course is rapid, with development of severe disability within 2 weeks to several months. Electromyographic and pathologic findings suggest that this is a disorder of connective tissue, affecting primarily the epimysium, tendons, and fasciae, and results in marked proliferation of fibrovascular connective tissue, with associated chondroid and osseous metaplasia.