Orthostatic Changes in Blood Pressure and Cognitive Status in the Elderly The Progetto Veneto Anziani Study
Orthostatic Changes in Blood Pressure and Cognitive Status in the Elderly The Progetto Veneto Anziani Study
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DOI：
10.1161/hypertensionaha.116.07334
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发表时间：
2016-08-01
期刊：
影响因子：
8.3
通讯作者：
Sergi, Giuseppe
中科院分区：
文献类型：
--
作者：
Curreri, Chiara;Giantin, Valter;Sergi, Giuseppe
我们研究了一组1408名老年受试者，以探索体位血压(BP；定义为立位性低血压或高血压)是否可以预测认知恶化的开始。直立性低血压定义为收缩压下降20 mm Hg或舒张压下降10 mm Hg，而直立性高血压定义为收缩压升高20 mm Hg。立位BP值按五分位数分组进行二次分析。考虑了两种认知评估：(1)认知障碍，即Mini-State考试成绩
We studied a cohort of 1408 older subjects to explore whether postural changes in blood pressure (BP; defined as orthostatic hypo-or hypertension) can predict the onset of cognitive deterioration. Orthostatic hypotension was defined as a drop of 20 mm Hg in systolic or 10 mm Hg in diastolic BP and orthostatic hypertension as a rise of 20 mm Hg in systolic BP. Orthostatic BP values were grouped into quintiles for secondary analyses. Two cognitive assessments were considered: (1) cognitive impairment, that is, Mini-Mental State Examination scores