The Promise of Whole Genome Pathogen Sequencing for the Molecular Epidemiology of Emerging Aquaculture Pathogens.

The Promise of Whole Genome Pathogen Sequencing for the Molecular Epidemiology of Emerging Aquaculture Pathogens.
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DOI:
10.3389/fmicb.2017.00121
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发表时间:
2017
影响因子:
5.2
通讯作者:
Feil EJ
Feil EJ
中科院分区:
生物学2区
文献类型:
--
作者:
Bayliss SC;Verner-Jeffreys DW;Bartie KL;Aanensen DM;Sheppard SK;Adams A;Feil EJ

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水产养殖是增长最快的粮食生产部门,该行业的可持续性对于全球粮食安全和经济福祉至关重要。传染病的管理是一项重大挑战。在这里,我们讨论水产养殖细菌和病毒病原体的全基因组测序为减轻疾病出现和传播提供的机会。通过比较,我们概述了测序技术如何改变具有公共卫生重要性的病原体的分子流行病学,强调面向社区的数据库和分析工具的重要性。
Aquaculture is the fastest growing food-producing sector, and the sustainability of this industry is critical both for global food security and economic welfare. The management of infectious disease represents a key challenge. Here, we discuss the opportunities afforded by whole genome sequencing of bacterial and viral pathogens of aquaculture to mitigate disease emergence and spread. We outline, by way of comparison, how sequencing technology is transforming the molecular epidemiology of pathogens of public health importance, emphasizing the importance of community-oriented databases and analysis tools.