Preferences for Long-Acting Pre-exposure Prophylaxis (PrEP), Daily Oral PrEP, or Condoms for HIV Prevention Among U.S. Men Who Have Sex with Men.
Preferences for Long-Acting Pre-exposure Prophylaxis (PrEP), Daily Oral PrEP, or Condoms for HIV Prevention Among U.S. Men Who Have Sex with Men.
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DOI：
10.1007/s10461-016-1565-9
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发表时间：
2017-05
影响因子：
4.4
通讯作者：
D'Aquila RT
中科院分区：
文献类型：
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作者：
Greene GJ;Swann G;Fought AJ;Carballo-Diéguez A;Hope TJ;Kiser PF;Mustanski B;D'Aquila RT
研究人员对512名美国男男性行为者（MSM，中位年龄：22岁）的艾滋病预防方法偏好进行了评估。大约90%的人在避孕套、每日口服暴露前预防（PrEP）和长效PrEP（通过注射或两种不同可见性的PrEP植入物之一）的成对比较中始终首选一种选择。最常用的是避孕套（33.8%），其次是不可见的植入物（21.5%）和口服PrEP（17.0%）;更多选择植入物报告了HIV风险。在仅比较四种PrEP选项的随访问题中，每日口服药丸和不可见的植入物是最常见的首选（分别为35.5%和34.3%），其次是注射（25.2%）和可见的植入物（4.3%）。一种归纳的、开放编码的方法确定，便利性、保护期限和隐私是PrEP方法选择的最常见原因，并与艾滋病毒风险的自我报告相关。根据隐私和其他对艾滋病毒风险最高者重要的问题定制PrEP产品开发可能会改善艾滋病毒预防。
HIV prevention method preferences were evaluated among 512 U.S. men who have sex with men (MSM; median age: 22 years). Approximately 90% consistently preferred one option across pairwise comparisons of condoms, daily oral pre-exposure prophylaxis (PrEP), and long-acting PrEP delivered via either an injectable or one of two types of PrEP implants differing in visibility. Condoms were most frequently preferred (33.8%), followed by non-visible implants (21.5%), and oral PrEP (17.0%); HIV risk was reported by more choosing implants. In a follow-up question comparing the four PrEP options only, daily oral pills and non-visible implants were most frequently preferred (35.5% and 34.3%, respectively), followed by injections (25.2%) and visible implants (4.3%). An inductive, open-coding approach determined that convenience, duration of protection, and privacy were the most commonly cited reasons for a PrEP method choice, and associated with self-report of HIV risk. Tailoring PrEP product development to privacy and other concerns important to those at highest HIV risk may improve HIV prevention.