Biological and molecular properties of yellow venom of the Amazonian coral snake Micrurus surinamensis
Biological and molecular properties of yellow venom of the Amazonian coral snake Micrurus surinamensis
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DOI：
10.1590/0037-8682-0408-2016
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发表时间：
2017-05-01
影响因子：
2
通讯作者：
Lopez Lozano, Jorge Luis
中科院分区：
文献类型：
--
作者：
Oliveira, Fabiana da Rocha;Nogueira Noronha, Maria Das Dores;Lopez Lozano, Jorge Luis
广泛分布在亚马逊地区的珊瑚蛇Microrurus surinamens具有神经毒性毒液。为了开发有效的抗毒素，对该毒液的生物学和分子特性进行表征是很重要的。方法：采用双向聚丙烯酰胺凝胶电泳法对苏云金杆菌毒素进行分析，并评价其体内神经毒性作用。结果与结论：蛇毒中的大部分蛋白质都有团块。
The coral snake Micrurus surinamensis, which is widely distributed throughout Amazonia, has a neurotoxic venom. It is important to characterize the biological and molecular properties of this venom in order to develop effective antitoxins. Methods: Toxins from the venom of M. surinamensis were analyzed by two-dimensional polyacrylamide gel electrophoresis and their neurotoxic effects in vivo were evaluated. Results and Conclusions: Most proteins in the venom had masses