Salt-, pH- and temperature-responsive semi-interpenetrating polymer network hydrogel based on poly(aspartic acid) and poly(acrylic acid)
Salt-, pH- and temperature-responsive semi-interpenetrating polymer network hydrogel based on poly(aspartic acid) and poly(acrylic acid)
复制标题
基于聚天冬氨酸和聚丙烯酸的盐、pH 和温度响应性半互穿聚合物网络水凝胶
DOI：
10.1016/j.polymer.2006.08.056
复制
发表时间：
2006-10
期刊：
影响因子：
4.6
通讯作者：
Zhao, Ying
中科院分区：
文献类型：
--
作者：
Kang, Juan;Tan, Tianwei;Zhao, Ying
本研究制备了一种新型的由聚天冬氨酸（PAsp）和聚丙烯酸（PAAc）组成的盐、pH和温度响应性半互穿网络（semi-IPN）水凝胶。PAsp/PAAc半互穿网络水凝胶为离子型水凝胶，其溶胀行为受溶胀介质的影响较大。通过傅里叶变换红外光谱（FTIR）和扫描电镜（SEM）研究了该三重响应性水凝胶的结构，并通过测定其在不同环境溶液中的平衡溶胀比，研究了其盐、温度和pH敏感性.结果表明，PAsp的引入改善了该水凝胶对无机盐（不同生理体液）、pH值和温度的响应性。此外，在可重复的溶胀和收缩期间，半互穿网络水凝胶显示出合适的机械强度。这种具有盐、pH和温度响应性的水凝胶在生物医学领域有着广泛的应用前景。
In this study, a novel salt-, pH- and temperature-responsive semi-interpenetrating network (semi-IPN) hydrogel, composed of poly(aspartic acid) (PAsp) and poly(acrylic acid) (PAAc), was prepared. PAsp/PAAc semi-IPN hydrogel being ionic in nature, the swelling behavior was significantly influenced by various swelling medium. The structure of the triply responsive hydrogel was studied by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM), and the salt-, temperature- and pH-sensitivities were investigated through measuring equilibrium swelling ratios in various environmental solutions. The results indicate that there is a structure of polyelectrolyte complex in the hydrogel, and that the responsive behaviors of this hydrogel to alternating changes in inorganic salt (different physiological bio-fluids), pH and temperature are improved because of the incorporation of PAsp. In addition, during the repeatable swelling and shrinkage period, the semi-IPN hydrogel shows suitable mechanical strength. The salt-, pH- and temperature-responsive hydrogel will have wider applications in biomedical areas.
登录
查看更多内容
影响因子：
--
作者：
R. Hernández;D. López;E. Pérez;C. Mijangos
通讯作者：
R. Hernández;D. López;E. Pérez;C. Mijangos
影响因子：
4.6
作者：
Zhao, Y;Su, HJ;Tan, TW
通讯作者：
Tan, TW
影响因子：
3
作者：
Y. M. Mohan;P. Murthy;J. Sreeramulu;K. Raju
通讯作者：
Y. M. Mohan;P. Murthy;J. Sreeramulu;K. Raju
影响因子：
4.6
作者：
F. Lionetto;A. Sannino;A. Maffezzoli
通讯作者：
F. Lionetto;A. Sannino;A. Maffezzoli
影响因子：
4.6
作者：
Smith, JR;Kholodovych, V;Welsh, WJ
通讯作者：
Welsh, WJ