Shear wave velocity imaging using transient electrode perturbation: phantom and ex vivo validation.
Shear wave velocity imaging using transient electrode perturbation: phantom and ex vivo validation.
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DOI：
10.1109/tmi.2010.2091412
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发表时间：
2011-03
影响因子：
10.6
通讯作者：
Madsen EL
中科院分区：
文献类型：
--
作者：
DeWall RJ;Varghese T;Madsen EL
本文提出了一种用于监测射频和微波消融过程的新型剪切波速成像技术——电极振动弹性成像技术。附着在消融针上的压电致动器被瞬时振动以产生高帧率跟踪的剪切波。采用峰值时间算法重建剪切波速，从而重建剪切模量的变化。通过有限元模型和超声模拟，模拟完全（幻影1）和部分消融（幻影2）区域的组织模拟模型，以及离体牛肝消融实验，证明了电极振动弹性成像的可行性。在模体实验中，观察到良好的边界描绘。在phantom 1中，剪切波速估计在机械测量值的7%以内，在phantom 2中在17%以内。在离体实验中也证明了良好的边界描绘。消融区域内的横波速度估计值高于机械测试估计值，但未经处理的组织估计值在机械测量值的20%以内。电极振动弹性学和电极位移弹性学的比较表明它们可以提供互补的信息。电极振动弹性成像技术有望作为一种成像方式，在消融过程中提供消融边界划定和定量信息。
This paper presents a new shear wave velocity imaging technique to monitor radio-frequency and microwave ablation procedures, coined electrode vibration elastography. A piezoelectric actuator attached to an ablation needle is transiently vibrated to generate shear waves that are tracked at high frame rates. The time-to-peak algorithm is used to reconstruct the shear wave velocity and thereby the shear modulus variations. The feasibility of electrode vibration elastography is demonstrated using finite element models and ultrasound simulations, tissue-mimicking phantoms simulating fully (phantom 1) and partially ablated (phantom 2) regions, and an ex vivo bovine liver ablation experiment. In phantom experiments, good boundary delineation was observed. Shear wave velocity estimates were within 7% of mechanical measurements in phantom 1 and within 17% in phantom 2. Good boundary delineation was also demonstrated in the ex vivo experiment. The shear wave velocity estimates inside the ablated region were higher than mechanical testing estimates, but estimates in the untreated tissue were within 20% of mechanical measurements. A comparison of electrode vibration elastography and electrode displacement elastography showed the complementary information that they can provide. Electrode vibration elastography shows promise as an imaging modality that provides ablation boundary delineation and quantitative information during ablation procedures.