Thoracic complications of illicit drug use: An organ system approach
Thoracic complications of illicit drug use: An organ system approach
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DOI：
10.1148/radiographics.22.suppl_1.g02oc01s119
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发表时间：
2002-10-01
期刊：
影响因子：
5.5
通讯作者：
Webb, WR
中科院分区：
文献类型：
--
作者：
Gotway, MB;Marder, SR;Webb, WR
非法药物使用构成一个主要的健康问题，并可能与各种胸部并发症有关。这些并发症因所用药物和给药途径而异。可能在引起胸部疾病中起作用的常见滥用药物包括可卡因、阿片类药物和甲基苯丙胺衍生物。脑内滥用的口服药物可能含有可能导致疾病的填充剂。胸部并发症可分为肺部、胸膜、纵隔、心血管和胸壁并发症。药物滥用的肺部并发症包括肺炎，心源性水肿、急性肺损伤、肺出血和吸入性肺炎。滑石粉等填充剂可能导致全腺泡肺气肿或高密度上叶聚集性肿块。使用非法药物的主要胸膜并发症是气胸。使用违禁药物引起的纵隔和心血管并发症包括肺气肿、心肌病、心肌梗塞、主动脉夹层和注射相关的假性动脉瘤。胸壁并发症包括椎间盘炎和脊椎骨髓炎、硬膜外脓肿、坏死性筋膜炎、肋软骨炎和脓毒性关节炎。对非法药物使用的胸部并发症进行分类可能有助于理解这些疾病并进行准确的诊断。(C)RSNA，2002年。
Illicit drug use constitutes a major health problem and may be associated with various thoracic complications. These complications vary depending on the specific drug used and the route of administration. Commonly abused drugs that may play a role in causing thoracic disease include cocaine, opiates, and methamphetamine derivatives. Intravenously abused oral medications may contain filler agents that may be responsible for disease. Thoracic complications may be categorized as pulmonary, pleural, mediastinal, cardiovascular, and chest wall complications. Pulmonary complications of drug abuse include pneumonia., cardiogenic edema, acute lung injury, pulmonary hemorrhage, and aspiration pneumonia. Filler agents such as talc may result in panacinar emphysema or high-attenuation upper-lobe conglomerate masses. The primary pleural complication of illicit drug use is pneumothorax. Mediastinal and cardiovascular complications of illicit drug use include pneumomediastinum, cardiomyopathy, myocardial infarction, aortic dissection, and injection-related pseudoaneurysms. Chest wall complications include diskitis and vertebral osteomyelitis, epidural abscess, necrotizing fasciitis, costochondritis, and septic arthritis. Categorization of thoracic complications of illicit drug use may facilitate understanding of these disorders and allow accurate diagnosis. (C) RSNA, 2002.