Prognostic implications of rest and exercise radionuclide ventriculography in patients with suspected or proven coronary heart disease.
Prognostic implications of rest and exercise radionuclide ventriculography in patients with suspected or proven coronary heart disease.
复制标题
休息和运动放射性核素心室造影对疑似或确诊冠心病患者的预后影响。
DOI：
10.1016/0167-5273(84)90298-5
复制
发表时间：
1984
影响因子：
3.5
通讯作者：
S. Kane
中科院分区：
文献类型：
--
作者：
A. Iskandrian;A. Hakki;J. Schwartz;H. Kay;S. Mattleman;S. Kane
评估休息和运动放射性核素心室造影在预测胸痛患者主要心脏事件中的价值。在随访长达51个月的219例患者中，42例发生主要心脏事件：12例（5.5%）死亡，5例（2.2%）持续非致死性心肌梗死，25例（11.4%）行冠状动脉旁路移植术。单因素和多因素生存分析显示，运动左心室射血分数是总主要事件的最佳预测因子，静息射血分数是死亡或非致死性心肌梗死的最佳预测因子。这两个变量在整个患者组和亚组中都是强有力的预测因素：有或没有q波梗死的患者，冠状动脉疾病的高概率患者和静息左心室功能异常的患者。因此，放射性核素血管造影提供了重要的预后数据，使医生能够根据随后的心脏事件对胸痛综合征患者进行分类。如果得到验证，该模型或对其进行修改，可以确定后续重大心脏事件的高风险患者，这些患者可以进行强化随访和治疗或进一步的有创性评估，以及后续重大心脏事件的低风险患者，标准随访将是合适的。
Rest and exercise radionuclide ventriculography were assessed for their value in predicting major cardiac events in patients with chest pain. Of 219 patients who were followed for up to 51 months, 42 had major cardiac events: 12 patients (5.5%) died, 5 (2.2%) sustained nonfatal myocardial infarction, and 25 (11.4%) had coronary arterial bypass grafting. Univariate and multivariate survival analysis revealed that exercise left ventricular ejection fraction was the best predictor for total major events and the resting ejection fraction to be the best predictor for death or nonfatal myocardial infarction. These two variables were strong predictors in the entire group of patients and in subgroups: patients with or without Q-wave infarction, patients with high probability of coronary artery disease and those with abnormal resting left ventricular function.Thus, radionuclide angiography provides important prognostic data that permits the physician to categorize patients with chest pain syndromes with respect to subsequent cardiac events. If validated, this model or a modification of it could identify patients at high risk of subsequent major cardiac events who are candidates for intensive follow up and therapy or further invasive evaluation, as well as patients at low risk of subsequent major cardiac events for whom standard follow up would be appropriate.
平衡放射性核素心室造影检测和评估冠状动脉疾病程度的直立和仰卧自行车运动的比较。
影响因子：
4.8
作者：
Freeman,MR;Berman,DS;Staniloff,H;Elkayam,U;Maddahi,J;Swan,HJ;Forrester,J
通讯作者：
Forrester,J