Chloro polyketides from the cultured fungus (Aspergillus) separated from a marine sponge
Chloro polyketides from the cultured fungus (Aspergillus) separated from a marine sponge
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DOI：
10.1016/0040-4039(96)00277-8
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发表时间：
1996-04-01
影响因子：
1.8
通讯作者：
Crews, P
中科院分区：
文献类型：
--
作者：
Abrell, LM;Borgeson, B;Crews, P
曲霉的盐水培养？ochraceus分离自印度-太平洋海绵Jaspis cf. Coriacea已经产生了两种新的含氯聚酮化合物，氯卡波酯A（1 B）和B（Ib）。这些化合物具有与carolic acid的整体结构相似性，carolic acid的生物合成已被深入研究。本文报道了氯卡罗内酯的结构和立体化学特征，并指出它们的α-亚甲基-γ-丁内酯与植物中的木姜子内酯和Mahubenolides相似。版权所有（C）1996 Elsevier Science Ltd
The salt water culture of Aspergillus ?ochraceus separated from the Indo-Pacific sponge Jaspis cf. coriacea has yielded two new chlorine containing polyketides, chlorocarolide A (1b) and B (Ib). These compounds have an overall structural analogy to carolic acid whose biosynthesis has been intensely studied. The structures and stereochemical features of the chlorocarolides are reported, Also noted are the similarities of their alpha-methylene-gamma-butyrolactones to those of the litsenolides and mahubenolides, both derived from plants. Copyright (C) 1996 Elsevier Science Ltd