The interfacial, emulsification and encapsulation properties of hydrophobically modified inulin
The interfacial, emulsification and encapsulation properties of hydrophobically modified inulin
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DOI：
10.1016/j.carbpol.2018.04.018
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发表时间：
2018-08-15
影响因子：
11.2
通讯作者：
Williams, P. A.
中科院分区：
文献类型：
--
作者：
Kokubun, S.;Ratcliffe, I.;Williams, P. A.
合成了菊粉的辛烯基和十二烯基琥珀酸酐衍生物（OSA-和DDSA-），测定了它们的溶液和界面性质，并与市售的烷基化菊粉Inutec SP1进行了比较。所有样品在超过临界浓度（临界聚集浓度）的溶液中形成胶束聚集体，并能够“溶解”疏水染料。他们还能够形成稳定的水包油（O/W）乳液，通过测量其液滴大小作为时间的函数来评估。采用溶剂蒸发法制备了高取代度的dddsa -菊粉包封β -胡萝卜素，制备的固体易于在模拟胃液中溶解。研究结果证实了这些材料在许多领域的潜在应用，包括药物输送、制药、中性药品、化妆品和个人护理。
Octenyl- and dodecenyl succinic anhydride derivatives (OSA- and DDSA-) of inulin have been synthesised and their solution and interfacial properties have been determined and compared to a commercially available alkylated inulin, Inutec SP1. All samples formed micellar aggregates in solution above a critical concentration (critical aggregation concentration) and were able to 'dissolve' a hydrophobic dye. They were also able to form stable oil-in-water (O/W) emulsions as assessed by measurements of their droplet size as a function of time. DDSA-inulin with a high degree of substitution was found to be effective at encapsulating beta carotene using the solvent evaporation method which yielded a solid which dissolved readily in simulated gastric fluid. The results confirm the potential application of these materials in a number of areas including, drug delivery, pharmaceuticals, neutraceuticals, cosmetics and personal care.