Neural mechanisms involved in mental imagery and observation of gait
Neural mechanisms involved in mental imagery and observation of gait
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DOI：
10.1016/j.neuroimage.2008.03.010
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发表时间：
2008-07-01
期刊：
影响因子：
5.7
通讯作者：
Fukuyama, Hidenao
中科院分区：
文献类型：
--
作者：
Iseki, Kazumi;Hanakawa, Takashi;Fukuyama, Hidenao
观察过程中的脑活动和步态的成像。16名受试者接受了3Tesla核磁共振扫描仪的扫描，同时观看了6种类型的视频片段：从第三人称视角观察步态运动(GO)，观察步态运动，观察站立姿势，观察行走过程中模拟视觉传入的视觉场景(VW)，以及GO和VW刺激的混杂版本。在大众的情况下，运动场景提供了一个虚拟的视觉环境，在这种环境中，受试者很容易想象出他们实际上是从第一人称角度行走的。一项行为学实验显示，在大众刺激的影响下，实际行走和想象行走时的步频存在相关性，这表明实际行走和步态想象具有共同的步态规划机制。VW刺激激活了背侧运动前皮质(PMD)、辅助运动区/扣带运动区(SMA/CMA)、海马旁回和皮质下核团。刺激GO可激活SMA、PMD、额下回和顶下小叶。此外，GO和VW的连接零测试显示，除视觉区域外，SMA/CMA和PMD中的共同活动，据报道在实际步态运动中也是活跃的。对步行或站立观察期间的活动的详细分析支持SMA和PMD to GO的特异性。这些发现表明，步态的运动规划中心，包括SMA和PMD，在想象(第一人称视角)和观察(第三人称视角)步态行为时都被激活。(C)2008 Elsevier Inc.保留所有权利。
Brain activity during observation and imagery of gait was investigated. Sixteen subjects were scanned with a 3-Tesla MRI scanner while viewing six types of video clips: observation of gait movement (GO) from the third-person perspective, observation of stepping movement, observation of standing posture, "virtual walking" (VW) that was observation of visual scenes mimicking the visual afferent during walking, and the scrambled version of the GO and VW stimuli. In the VW condition, moving scenes provided a virtual visual environment in which subjects easily imagined as if they were actually walking from the first-person perspective. A behavioral experiment revealed a correlation of cadence during actual walking with that during imaginary walking under the influence of the VW stimuli, indicating that a gait planning mechanism was shared by actual walking and gait imagery. The VW condition activated the dorsal premotor cortex (PMd), supplementary motor area/cingulate motor area (SMA/ CMA), parahippocampal gyrus, and subcortical nuclei. The GO stimuli yielded activation of the SMA, PMd, inferior frontal gyrus, and inferior parietal lobule. Moreover, the conjunction null test of GO and VW revealed common activity in the SMA/CMA and PMd, which were reportedly active during actual gait movement, in addition to visual areas. Detailed analyses of activity during stepping or standing observation supported the specificity of the SMA and PMd to GO. These findings suggest that motor planning centers of gait, including the SMA and PMd, are activated during both imagination (firstperson perspective) and observation (third-person perspective) of gait behaviors. (C) 2008 Elsevier Inc. All rights reserved.