Stable T-cell population expressing an effector cell surface phenotype in the lungs of mice chronically infected with Mycobacterium tuberculosis
Stable T-cell population expressing an effector cell surface phenotype in the lungs of mice chronically infected with Mycobacterium tuberculosis
复制标题
DOI：
10.1128/iai.72.1.570-575.2004
复制
发表时间：
2004-01-01
影响因子：
3.1
通讯作者：
Orme, IM
中科院分区：
文献类型：
--
作者：
Junqueira-Kipnis, AP;Turner, J;Orme, IM
对慢性结核分枝杆菌感染C57BL/6小鼠肺中积累的T细胞亚群的分析显示，CD4和CD8 T细胞群表达的细胞表面表型与效应T细胞一致，并且这些细胞中有很大一部分处于分泌γ干扰素的过程中。
Analysis of T-cell subsets accumulating in the lungs of C57BL/6 mice chronically infected with Mycobacterium tuberculosis revealed that both CD4 and CD8 T-cell populations expressed a cell surface phenotype consistent with that of effector T cells and that a significant proportion of these cells were in the process of secreting gamma interferon.